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TranscriptomicsComplexity of Murine Cardiomyocyte miRNA Biogenesis, Sequence Variant Expression and Function
microRNAs (miRNAs) are critical to heart development and disease. Emerging research indicates that regulated precursor processing can give rise to an unexpected diversity of miRNA variants. We subjected small RNA from murine HL-1 cardiomyocyte cells to next generation sequencing to investigate the r...
ORGANISM(S): Mus musculus 
2012-07-20 | E-GEOD-39531 | biostudies-arrayexpress
UnknownDose-limiting toxicity after hypofractionated dose-escalated radiotherapy in non-small-cell lung cancer.
Not available
S-EPMC3837093 | biostudies-literature
TranscriptomicsAutotaxin and its product lysophosphatidic acid suppress brown adipose differentiation and promote diet-induced obesity in mice
Brown adipose tissue (BAT) is a thermogenic organ that dissipates stored energy as heat to maintain body temperature in infants and small mammals. This process may also provide protection from development of diet-induced obesity. We found that the bioactive lipid mediator lysophosphatidic acid (LP...
ORGANISM(S): Mus musculus 
2011-06-01 | E-GEOD-26442 | biostudies-arrayexpress
TranscriptomicsMre11 suppresses replication stress and gene amplification proficiency
Gene amplification, copy-number increases of particular genes and surrounding genomic segments, promotes cancer progression and acquired therapy resistance. Thus, understanding genetic traits that confer gene amplification proficiency is important. The primary step for gene amplification is sponta...
ORGANISM(S): Cricetulus griseus 
2015-03-05 | E-GEOD-59487 | biostudies-arrayexpress
UnknownOverall Survival and Long-Term Safety of Nivolumab (Anti-Programmed Death 1 Antibody, BMS-936558, ONO-4538) in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer.
Not available
S-EPMC4672027 | biostudies-literature
GenomicsMaternal Nutrition Induces Pervasive Gene Expression Changes but no Detectable DNA Methylation Differences in the Liver of Adult Offspring [selected loci]
Aims: Epidemiological and animal studies have shown that maternal diet can influence metabolism in adult offspring. However, the molecular mechanisms underlying these changes remain poorly understood. Here, we aim to explore phenotypes induced by maternal obesity in a mouse model and examine gene ex...
ORGANISM(S): Mus musculus 
2014-03-04 | E-GEOD-52267 | biostudies-arrayexpress
GenomicsMaternal Nutrition Induces Pervasive Gene Expression Changes but no Detectable DNA Methylation Differences in the Liver of Adult Offspring [RRBS]
Aims: Epidemiological and animal studies have shown that maternal diet can influence metabolism in adult offspring. However, the molecular mechanisms underlying these changes remain poorly understood. Here, we aim to explore phenotypes induced by maternal obesity in a mouse model and examine gene ex...
ORGANISM(S): Mus musculus 
2014-03-04 | E-GEOD-52266 | biostudies-arrayexpress
UnknowniCatCare 2025 consensus guidelines on the diagnosis and management of diabetes mellitus in cats.
Not available
S-EPMC12612538 | biostudies-literature
UnknownComparison of genetic variability at multiple loci across the genomes of the major subtypes of Kaposi's sarcoma-associated herpesvirus reveals evidence for recombination and for two distinct types of open reading frame K15 alleles at the right-hand end.
Not available
S-EPMC112749 | biostudies-literature
TranscriptomicsSoy LGI Protein NILs, seed fill
Evaluation of transcripts from soybean seed tissue during seed fill for a pair of near-isogenic lines contrasting in seed protein and oil and carrying an introgression at the linkage group I protein QTL region. ****[PLEXdb(http://www.plexdb.org) has submitted this series at GEO on behalf of the or...
ORGANISM(S): Glycine max 
2011-11-22 | E-GEOD-33408 | biostudies-arrayexpress
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