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TranscriptomicsE-cadherin and EMT regulation by bHLH factors: a new role for the class I gene E2-2 (TCF4) and its comparison with E47.
Loss of expression of the cell-cell adhesion molecule E-cadherin is an essential event for epithelial-mesenchymal transition (EMT), a process that allows cell migration in the developing embryo and during tumour invasion. Transcriptional repression has emerged as the main mechanism responsible for E...
ORGANISM(S): Canis lupus familiaris 
2010-06-24 | E-GEOD-9145 | biostudies-arrayexpress
TranscriptomicsE-cadherin and EMT regulation by E47 transcription represor
Expression profile analysis in MDCK-E47 cells in comparisom with MDCK CMV control cells Keywords: Genetic Modification (overexpression of E-cadherin repressors) The Oncochip microarray platform v1.1 contains 9,726 clones corresponding to 6,386 different genes, and it includes 2,489 duplicate clones....
ORGANISM(S): Canis lupus familiaris 
2010-06-24 | E-GEOD-9147 | biostudies-arrayexpress
TranscriptomicsSynergy between plasminogen activator inhibitor-1 and Snail in tumoral migration
Snail, a family of transcriptional repressors implicated in cell movement, has been correlated with tumour invasivity. The Plasminogen Activation system (PAs), including urokinase (uPA), its receptor (uPAR), and its inhibitor (PAI-1), also plays a key role in cancer invasion and metastasis, either t...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-10395 | biostudies-arrayexpress
TranscriptomicsZeb1 and Snail1 engage miR-200f transcriptional and epigenetic regulation during EMT
Cell plasticity is emerging as a key regulator of tumor progression and metastasis. During carcinoma dissemination epithelial cells undergo epithelial to mesenchymal transition (EMT) processes characterized by the acquisition of migratory/invasive properties, while the reverse, mesenchymal to epithe...
ORGANISM(S): Canis lupus familiaris 
2014-09-09 | E-GEOD-61217 | biostudies-arrayexpress
TranscriptomicsBacterial antisense RNAs are mainly the product of transcriptional noise
Cis-encoded antisense RNAs (asRNAs) are widespread along bacterial transcriptomes. However, the role of the vast majority of these RNAs remains unknown, and there is an ongoing discussion as to what extent these transcripts are the result of transcriptional noise. We show, by comparative transcripto...
ORGANISM(S): Mycoplasma pneumoniae 
2016-01-18 | E-MTAB-4081 | biostudies-arrayexpress
ModelsLlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case1
LlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case1 Three putative effects of the asRNAs were considered in this study: in case 1  (this model) , the binding of the asRNA to the corresponding mRNA induces degradation of the duplex. In case 2, the binding of the ...
2017-05-18 | MODEL1511170000 | BioModels
ModelsLlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case2
LlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case1 Three putative effects of the asRNAs were considered in this study: in case 1 , the binding of the asRNA to the corresponding mRNA induces degradation of the duplex. In case 2   (this model)   the binding o...
2017-05-18 | MODEL1511170001 | BioModels
ModelsLlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case3
LlorénsRico2016 - Effects of cis-Encoded antisense RNAs (asRNAs) - Case3 Three putative effects of the asRNAs were considered in this study: in case 1, the binding of the asRNA to the corresponding mRNA induces degradation of the duplex. In case 2, the binding of the asRNA to...
2017-05-18 | MODEL1511170002 | BioModels
UnknownReplication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of Trypanosoma cruzi.
Not available
S-EPMC5161316 | biostudies-literature
UnknownLosartan and isoproterenol promote alterations in the local renin-angiotensin system of rat salivary glands.
Not available
S-EPMC6530859 | biostudies-literature
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