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ProteomicsSleep fragmentation exacerbates cardiac microvascular endothelial cell cuproptosis via promoting neutrophil extracellular trap formation in myocardial ischemia-reperfusion injury
Objective: This study aimed to investigate the relationship between sleep disorders and cardiac microvascular injury in myocardial ischemia-reperfusion injury (MI/RI) mice. Design: Mice were placed in a sleep deprivation chamber. The sweep bar moved along the bottom of the cage every 2 min during th...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-08 | PXD066510 | Pride
Myocardial ischemia-reperfusion injury  sleep fragmentation  neutrophil extracellular traps  cardiac microvascular endothelial cells  cuproptosis 
UnknownMitochondria-targeted antioxidant mitoquinone mitigates vitrification-induced damage in mouse ovarian tissue by maintaining mitochondrial homeostasis via the p38 MAPK pathway.
Not available
S-EPMC11657888 | biostudies-literature
UnknownBerberine targets the PI3Kα LYS672 site to suppress the PI3K/Akt/NF-κB axis and modulate microglial functional states after intracerebral hemorrhage.
Not available
S-EPMC13634748 | biostudies-literature
ProteomicsProteomic Analysis of Hypoxic Human Lung Epithelial Cells
H441 cell proteome was sequenced via SILAC and LC-MS/MS method to identify hypoxia-responsive proteins
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-05-15 | MSV000081087 | MassIVE
TranscriptomicsA transcriptomic analysis of super-hybrid rice LYP9 and its parental lines
Using a whole-genome oligonucleotide microarray designed based on known and predicted indica rice genes, we investigated transcriptome profiles in developing leaves and panicles of super hybrid rice LYP9 and its parental cultivar 93-11 and PA64s. We detected 22,266 expressed genes out of 36,926 tota...
ORGANISM(S): Oryza sativa 
2009-04-22 | E-GEOD-14729 | biostudies-arrayexpress
TranscriptomicsComparison of genomic H3K9ac status in CD4 T cells with diverse progress of chronic hepatitis B
Histone 3 lysine 9 acetylation (H3K9ac) at transcription initiation sites is a well known marker for actively initiating and transcribing genes.The purpose of the present study was to investigate the association between H3K9ac and diverse progress of HBV infection. We employed chromatin immunoprecip...
ORGANISM(S): Homo sapiens 
2012-08-28 | E-GEOD-40365 | biostudies-arrayexpress
ProteomicsEarly Proteomic and Metabolomic Signatures in Diabetes Associated with Progression to Diabetic Retinopathy Over 1–2 Years
In this study, we leveraged 15 paired plasma samples collected from the same individuals who exhibited rapid progression from DM to DR within 1-2 years and conducted integrated proteomic and metabolomic analyses to investigate molecular changes associated with disease progression. Key proteins were ...
ORGANISM(S): Homo Sapiens 
2026-05-19 | PXD078538 |
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