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MetabolomicsMethionine Intervention Induces PD-L1 Expression to Enhance the Immune Checkpoint Therapy Response in MTAP-deleted Osteosarcoma
Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we have identified a subgroup of OS with methylthioadenosine phosphorylase (MTAP) deletion, which contributes to ICT r...
2026-06-09 | MTBLS11985 | MetaboLights
MetabolomicsMetabolite signatures of diverse Camellia sinensis tea populations
Tea plants (Camellia sinensis) present an excellent system to study evolution and diversification of specialized metabolites due to their abundance in classes, numbers and contents. A large number of tea cultivars have been cultivated throughout the world not only because of their adaption to differ...
2020-10-05 | MTBLS1405 | MetaboLights
ProteomicsPreferential phosphorylation on old histones during early mitosis in human cells
How histone posttranslational modifications (PTMs) are inherited through cell cycle remains poorly understood. Canonical histones are made in the S phase of cell cycle. Combining mass spectrometry-based technologies and stable isotope labeling by amino acids in cell culture (SILAC), we interrogate t...
ORGANISM(S): Homo sapiens (Human) 
2016-06-01 | PXD003709 | Pride
Mass spectrometry Mitosis Histone modifications Cell cycle Histone phosphorylation 
UnknownLin- PU.1dim GATA-1- defines haematopoietic stem cells with long-term multilineage reconstitution activity.
Not available
S-EPMC10623959 | biostudies-literature
UnknownPressure-stabilized divalent ozonide CaO3 and its impact on Earth's oxygen cycles.
Not available
S-EPMC7499259 | biostudies-literature
TranscriptomicsRNA-seq of mouse adipose stem and progenitor cells
Population control for the scRNA-seq based analysis a well-established fraction of mouse subcutaneous adipose-derived stromal vascular fraction (SVF) cells that is generally considered to harbour adipogenic stem and progenitor cells (ASPCs). We collected Lin- (CD31- CD45- TER119-) CD29+ CD34+ SCA1+ ...
ORGANISM(S): Mus musculus 
2018-05-01 | E-MTAB-5818 | biostudies-arrayexpress
Proteomicsciliary proteins of Chlamydomonas
We revealed the systematic regulation of ciliary composition in WT and the transition zone muntants.
ORGANISM(S): Chlamydomonas reinhardtii 
2022-08-12 | PXD033090 | Pride
Transition zone Cilia 
UnknownThe Response of Growth and Transcriptome Profiles of Tea Grey Blight Disease Pathogen Pestalotiopsis theae to the Variation of Exogenous L-Theanine.
Not available
S-EPMC10971465 | biostudies-literature
TranscriptomicsGlobal analysis of metastasis-associated gene expression in the primary cultures from clinical specimens of ccRCC
Metastatic clear cell renal cell carcinoma (ccRCC) has a poor prognosis and unpredictable course and there are no molecular markers that reliably predict ccRCC metastasis. In this study, specimens from 84 patients with ccRCC were directly cultured in vitro. The primary cultures from 38 of 94 specime...
ORGANISM(S): Homo sapiens 
2008-08-27 | E-GEOD-11072 | biostudies-arrayexpress
UnknownThe intersection of bronchoscopy and extracorporeal membrane oxygenation.
Not available
S-EPMC8411169 | biostudies-literature
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