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MetabolomicsMethionine Intervention Induces PD-L1 Expression to Enhance the Immune Checkpoint Therapy Response in MTAP-deleted Osteosarcoma
Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we have identified a subgroup of OS with methylthioadenosine phosphorylase (MTAP) deletion, which contributes to ICT r...
2026-06-09 | MTBLS11985 | MetaboLights
MetabolomicsNatural polymorphism of ZmICE1 contributes to amino acid metabolism that impacts cold tolerance in maize

Cold stress negatively affects maize (Zea mays L.) growth, development and yield. Metabolic adjustments contribute to the adaptation of maize under cold stress. We show here that the transcription factor INDUCER OF CBF EXPRESSION 1 (ZmICE1) plays a prominent role in reprogramming amino a...

2022-10-31 | MTBLS4404 | MetaboLights
UnknownNovel procedure of CO2 capture of the CaO sorbent activator on the reaction of one-part alkali-activated slag.
Not available
S-EPMC8696962 | biostudies-literature
MetabolomicsPlasma metabolome alteration in dairy cows with left displaced abomasum before and after surgical correction
Left displaced abomasum (LDA) leads to substantial changes in the metabolism of dairy cows. Surgical correction of LDA can rapidly improve the health of cows; however, changes in metabolism following surgery are rarely described. To investigate the changes of plasma metabolome in cows with LDA befor...
2022-08-17 | MTBLS4126 | MetaboLights
UnknownThe complete mitochondrial genome of Triplophysa nanpanjiangensis Zhu and Cao 1988 (Cypriniformes: Nemacheilidae).
Not available
S-EPMC10776044 | biostudies-literature
UnknownThe profibrotic effects of MK-8617 on tubulointerstitial fibrosis mediated by the KLF5 regulating pathway.
Not available
S-EPMC6902673 | biostudies-literature
UnknownLoad-dependent inverted U-shaped connectivity of the default mode network in schizophrenia during a working-memory task: evidence from a replication functional MRI study.
Not available
S-EPMC9524478 | biostudies-literature
TranscriptomicsThe effect of cold and hydrogen peroxide in wheat.
One day cold (14 and 19 °C) and hydrogen peroxide (H2O2) treatment of wheat (Triticum aestivum ssp. aestivum L.) variety Chinese Spring and two chromosome 5A substitution lines of Chinese Spring, Chinese Spring(T. ae. ssp. aestivum L. Cheyenne 5A) and Chinese Spring(T. ae. ssp. spelta L. 5A).
ORGANISM(S): Triticum aestivum 
2018-09-28 | E-MTAB-6627 | biostudies-arrayexpress
UnknownThe complete chloroplast genome sequence of <i>Zehneria japonica</i> (Thunb.) H. Y. Liu (Cucurbitaceae), a medicinal plant.
Not available
S-EPMC12523466 | biostudies-literature
MetabolomicsModulation of liver metabolism and gut microbiota by Alhagi-honey alleviated heat stress-induced liver damage

Alhagi-honey (AH) is a well-established traditional ethnic medicine with advantageous effects against diarrhea and headaches. We aim to explore the preventive effect of AH on liver damage induced by heat stress (HS) and its underlying mechanism. HS models were established by thermostat, and mice ...

2024-09-23 | MTBLS10021 | MetaboLights
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