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MetabolomicsA novel targeted/untargeted GC-Orbitrap metabolomics methodology applied to Candida albicans and Staphylococcus aureus biofilms

INTRODUCTION: Combined infections from Candida albicans and Staphylococcus aureus are a leading cause of death in the developed world. Evidence suggests that Candida enhances the virulence of Staphylococcus - hyphae penetrate through tissue bar...

2017-02-20 | MTBLS370 | MetaboLights
ProteomicsMutagenesis of Key Phosphodiesterases in Toxoplasma gondii Demonstrates the Plasticity and Therapeutic Potential of Cyclic Nucleotide Signaling
Cyclic nucleotide signaling is pivotal to the asexual growth of T. gondii; however, little do we know about its counter-regulation in this parasite. We identified 18 phosphodiesterase (PDE1-18) enzymes, most of which form apicomplexan-specific clades and lack typical regulatory motifs found in mamma...
ORGANISM(S): Cellular Organisms 
2023-02-22 | PXD032173 | JPOST Repository
TranscriptomicsTranscriptome analysis of pancreatic cancer cell line that differ in metastatic potential
Two pancreatic cancer cell lines with different metastatic and growth potential were compared under hypoxic conditions and under normal atmospheric oxygen pressure. The FG cell lines shows very few metastases and slow growth in mouse xenograft models. L3.6pl, derived from FG by cycles re-implantatio...
ORGANISM(S): Homo sapiens 
2010-09-30 | E-GEOD-9350 | biostudies-arrayexpress
UnknownRecruitment of glycosyl hydrolase proteins in a cone snail venomous arsenal: further insights into biomolecular features of Conus venoms.
Not available
S-EPMC3296996 | biostudies-literature
UnknownAssociation Between Initial Route of Fluoroquinolone Administration and Outcomes in Patients Hospitalized for Community-acquired Pneumonia.
Not available
S-EPMC4901867 | biostudies-literature
ProteomicsM.tuberculosis - Whole organism, absolute concentration (Schubertetal,cellhostmicrobe2014)
abundance based on absolute concentration, Interaction consistency score: 1.0, Coverage: 46
ORGANISM(S): 83332 
2014-00-00 | 2118471723 | PAXDB
ProteomicsMtb_H37Rv_ETHZ
Mtb_H37Rv_OGE24
ORGANISM(S): Mycobacterium Tuberculosis 
2013-12-31 | PAe003619 | PeptideAtlas
TranscriptomicsCYP78A9- produced signal is involved in Arabidopsis reproductive development
Transcriptional responses to CYP78A9 activity in Arabidopsis thaliana. Microarray experiment comparing es1-D (Arabidopsis activation tagging mutant that overexpress a P450 named CYP78A9) and wild type (Ws-3)closed floral buds from young primary inflorescences.
ORGANISM(S): Arabidopsis thaliana 
2013-04-24 | E-MEXP-3770 | biostudies-arrayexpress
GenomicsChIP-seq for the identification of enhancer and super enhancers in Acute Myeloid Leukemia cells with a 3q-aberration
To infer enhancers and super enhancers in Acute Myeloid Leukemia (AML) Cell lines with a 3q-aberration we determined regions enriched for H3K27AC, H3K4ME3, H3K4ME1, P300, and BRD4 in MOLM1. Additionally we determined regions enriched for P300 and BRD4 in the cell line Mutz3 which also harbors a 3q-a...
ORGANISM(S): Homo sapiens 
2014-04-03 | E-MTAB-2224 | biostudies-arrayexpress
TranscriptomicsTargeting the EWS/ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma
Ewing sarcomas (ES) are highly malignant, osteolytic bone or soft tissue tumors, which are characterized by early metastasis into lung and bone. Genetically, ES are defined by balanced chromosomal EWS/ETS translocations, which give rise to chimeric proteins (EWS-ETS) that generate an oncogenic trans...
ORGANISM(S): Homo sapiens 
2015-12-08 | E-GEOD-72673 | biostudies-arrayexpress
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