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TranscriptomicsDose response of carbon monoxide treatment of M. tuberculosis
Transcriptional profiling of M. tuberculosis growing in log phase treated with various concentrations of carbon monoxide versus untreated controls Keywords: Dose response Two condition experiment, CO treated cells at 2000, 200 and 20 ppm versus untreated controls. Biological replicates: 2 replicates...
ORGANISM(S): Mycobacterium tuberculosis 
2008-05-29 | E-GEOD-11095 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse RAW 264.7 macrophages treated with carbon monoxide and lipopolysaccharide
Murine RAW 264.7 peritoneal macrophages were treated with 250 ppm Carbon monoxide (CO) for 3 hours prior to the addition of LPS (10 ng/ml) and then for the subsequent 4 hours of the study. Air-treated cells were maintained for the same time without CO. Total RNA was harvested at 0, 15, 30, 60, 120 a...
ORGANISM(S): Mus musculus 
2007-12-04 | E-GEOD-1906 | biostudies-arrayexpress
TranscriptomicsAssessment of the carbon monoxide metabolism of the hyperthermophilic sulfate-reducing archaeon Archaeoglobus fulgidus VC-16 by comparative transcriptome analyses
The metabolic versatile hyperthermophilic dissimilatory sulfate-reducing archaeon, Archaeoglobus fulgidus VC-16, both utilize carbon monoxide as energy source and is highly resistant to toxic effects of CO. This metabolic capacity was investigated by transcriptional response to growth with CO of cul...
ORGANISM(S): Archaeoglobus fulgidus VC-16 
2015-04-30 | E-MTAB-3035 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiles of yeast on acetate exposed to pure nitrogen or carbon monoxide
Oxygen lack of various severity can force many organisms to enter into recoverable hypometabolic states. To better understand how organisms cope with oxygen deprivation, our lab had previously shown that when challenged with anoxia, both the nematode Caenorhabditis elegans and embryos of the zebrafi...
ORGANISM(S): Saccharomyces cerevisiae 
2008-07-08 | E-GEOD-12004 | biostudies-arrayexpress
TranscriptomicsRole of M. tuberculosis in CO sensing
This SuperSeries is composed of the following subset Series: GSE11095: Dose response of carbon monoxide treatment of M. tuberculosis GSE11096: Role of M. tuberculosis dosS and dosT in CO sensing Refer to individual Series
ORGANISM(S): Mycobacterium tuberculosis 
2008-05-28 | E-GEOD-10897 | biostudies-arrayexpress
TranscriptomicsRole of M. tuberculosis dosS and dosT in CO sensing
Transcriptional profiling of M. tuberculosis dosR and dosS mutants and wild type growing in log phase treated with carbon monoxide or nitric oxide versus untreated controls Keywords: Genetic modification Two condition experiment, DETANO treated cells at 100 uM or CO treated cells at 20000 ppm versus...
ORGANISM(S): Mycobacterium tuberculosis 
2008-05-28 | E-GEOD-11096 | biostudies-arrayexpress
TranscriptomicsEffect of carbon monoxide and the CO sensor CooA on gene expression in Desulfovibrio vulgaris Hildenborough
Investigating the role of carbon monoxide and a CO sensor protein CooA in the physiology of Desulfovibrio vulgaris Hildenborough using whole genome expression analysis Comparison of whole genome expression changes in the wild type and a strain deleted for CooA (DVU2097) in the presence and absence o...
ORGANISM(S): Desulfovibrio vulgaris str. Hildenborough 
2012-07-30 | E-GEOD-36770 | biostudies-arrayexpress
TranscriptomicsInterfering with Proximal TLR4 to NF-kappaB Signal Transduction in Human Monocytes
This study investigated the global effect of carbon monoxide (CO) gas (250 ppm) on LPS- induced gene expression in THP-1 cells. CO predominantly suppresses LPS-induced gene response. Of the CO-suppressed genes, 18% were transcription factors and most others were cytokines, chemokines and immune resp...
ORGANISM(S): Homo sapiens 
2010-06-08 | E-GEOD-16193 | biostudies-arrayexpress
GenomicsAdaptive laboratory evolution of Eubacterium limosum ATCC 8486 on carbon monoxide
Adaptive laboratory evolution of Eubacterium limosum ATCC 8486 on carbon monoxide
PRJEB34640 | ENA
TranscriptomicsIschemia reperfusion injury (IRI) in organ transplantation and the effects of carbon monoxide treatment
Ischemia reperfusion injury (IRI) in organ transplantation remains a significant problem with limited alternative therapeutic options. Organs that undergo significant damage during IRI, particularly those enduring long warm ischemia times, undergo significant delayed graft function (DGF) after reper...
ORGANISM(S): Sus scrofa 
2009-01-20 | E-GEOD-14373 | biostudies-arrayexpress
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