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TranscriptomicsTranscription profiling of S. cerevisiae grown in acetate, ethanol and maltose limited conditions to investigate transcriptional regulation in controlling fluxes in central carbon metabolism
In contrast to batch cultivation, chemostat cultivation allows the identification of carbon source responses without interference by carbon-catabolite repression, accumulation of toxic products, and differences in specific growth rate. This study focuses on the yeast Saccharomyces cerevisiae, grown ...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-8895 | biostudies-arrayexpress
TranscriptomicsComparative RNA-Seq of Cupriavidus necator H16, formerly Ralstonia eutropha H16, grown in minimal media with 3-hydroxypropionic acid (3-HP) or fructose as sole carbon source.
3-hydroxypropionic acid (3-HP) is a promising platform chemical with various industrial applications. Several metabolic routes to produce 3-HP from organic substrates such as sugars or glycerol have been implemented in yeast, enterobacterial species and other microorganisms. In this work, we investi...
ORGANISM(S): Cupriavidus necator H16 
2019-03-31 | E-MTAB-7701 | biostudies-arrayexpress
MetabolomicsDIATAGeR: Triacylglycerol Annotation of Data-Independent Acquisition based Lipidomics

Triacylglycerols (TGs) are the most abundant lipids in the human body and the primary source of energy storage. Altered TGs are implicated in metabolic syndrome and detailed structural information may provide novel insights into diseases pathology. TGs are comprised of three fatty acyls with vari...

2025-03-04 | MTBLS11927 | MetaboLights
ProteomicsEngineering a new-to-nature cascade for phosphate-dependent formate to formaldehyde conversion in vitro and in vivo
To realize a carbon-neutral bioeconomy, the concept of electrobiocatalysis has been developed, in which CO2 is first chemically reduced to formate and subsequently assimilated by enzymatic cascades or engineered microbes. A key step in the assimilation of formate is its reduction into formaldehyde, ...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2023-03-22 | MSV000091532 | MassIVE
TranscriptomicsStructural, Functional and Molecular Impact on the Cardiovascular System in ApoE-/- Mice Exposed to Aerosol from modified risk tobacco products, the Carbon Heated Tobacco Product 1.2 and the Tobacco Heating System 2.2 compared to Cigarette Smoke effects (mRNA data).
AIM: To investigate the molecular, structural, and functional impact of aerosols from two heat-not-burn-based MRTPs, the Carbon Heated Tobacco Product (CHTP) 1.2 and Tobacco Heating System (THS) 2.2, compared with that of cigarette mainstream smoke (CS) on the cardiovascular system of ApoE-/- mice. ...
ORGANISM(S): Mus musculus 
2021-08-16 | E-MTAB-7980 | biostudies-arrayexpress
TranscriptomicsStructural, Functional and Molecular Impact on the Cardiovascular System in ApoE-/- Mice Exposed to Aerosol from modified risk tobacco products, the Carbon Heated Tobacco Product 1.2 and the Tobacco Heating System 2.2 compared to Cigarette Smoke effects (miRNA data).
AIM: To investigate the molecular, structural, and functional impact of aerosols from two heat-not-burn-based MRTPs, the Carbon Heated Tobacco Product (CHTP) 1.2 and Tobacco Heating System (THS) 2.2, compared with that of cigarette mainstream smoke (CS) on the cardiovascular system of ApoE-/- mice. ...
ORGANISM(S): Mus musculus 
2021-08-16 | E-MTAB-7981 | biostudies-arrayexpress
UnknownTrial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3.
Not available
S-EPMC4872347 | biostudies-literature
TranscriptomicsTranscription profiling of S. cerevisiae treated with absence of oxygen or depletion of ATP to investigate control of glycolytic enzyme fluxes
Metabolic fluxes may be regulated "hierarchically," e.g., by changes of gene expression that adjust enzyme capacities (V(max)) and/or "metabolically" by interactions of enzymes with substrates, products, or allosteric effectors. In the present study, a method is developed to dissect the hierarchical...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-9232 | biostudies-arrayexpress
UnknownNanoFlares for the detection, isolation, and culture of live tumor cells from human blood.
Not available
S-EPMC4260589 | biostudies-literature
TranscriptomicsGenetic Manipulation of Putrescine Biosynthesis Reprograms the Cellular Transcriptome and the Metabolome
Background: With the increasing interest in metabolic engineering of plants using various genetic manipulation and gene editing technologies in order to enhance their growth, nutritional value and environmental adaptation, a major concern is the potential of broad and distant effects of manipulating...
ORGANISM(S): Populus maximowiczii x Populus nigra 
2016-03-24 | E-GEOD-79420 | biostudies-arrayexpress
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