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TranscriptomicsBroad epigenetic signature of maternal care in the brain of adult rats
This SuperSeries is composed of the following subset Series: GSE20714: Broad epigenetic signature of maternal care in the brain of adult rats (DNA methylation and H3K9 acetylation profiles) GSE20717: Broad epigenetic signature of maternal care in the brain of adult rats (expression) Refer to individ...
ORGANISM(S): Rattus norvegicus 
2011-03-09 | E-GEOD-20840 | biostudies-arrayexpress
TranscriptomicsBroad epigenetic signature of maternal care in the brain of adult rats (DNA methylation and H3K9 acetylation profiles)
Maternal care is associated with long-term effects on behavior and epigenetic programming of the NR3C1 (GLUCOCORTICOID RECEPTOR) gene in the hippocampus of both rats and humans. However, epigenetic changes at a single gene promoter are unlikely to account for the range of responses to the early life...
ORGANISM(S): Rattus norvegicus 
2011-03-09 | E-GEOD-20714 | biostudies-arrayexpress
MetabolomicsMetabolic phenotyping of urine from a dementia research cohort
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
TranscriptomicsNetwork analysis identifies proinflammatory plasma cell polarization for secretion of ISG15 in human autoimmunity
Plasma cells (PCs) as effectors of humoral immunity produce immunoglobulins to match pathogenic insult. However, emerging data suggests more diverse roles for PCs as regulators of immune and inflammatory responses via secretion of factors other than immunoglobulins. The extent to which such response...
ORGANISM(S): Homo sapiens 
2016-07-22 | E-GEOD-75007 | biostudies-arrayexpress
TranscriptomicsSPIB and BATF provide alternate determinants of IRF4 occupancy in Diffuse Large B-cell Lymphoma linked to disease heterogeneity.
Gene expression from OCI-LY3 cells 48hrs after knock down of SPIB. 2 samples analysed (scramble and siRNA knock down), each with a single repeat.
ORGANISM(S): Homo sapiens 
2014-06-03 | E-GEOD-50015 | biostudies-arrayexpress
GenomicsSPIB and BATF provide alternate determinants of IRF4 occupancy in Diffuse Large B-cell Lymphoma linked to disease heterogeneity
ChIP-seq data for the transcription factors (TFs) IRF4, PU.1 and SPIB from the cell lines OCI-LY3, OCI-LY10 and H929, and BATF from the cell lines OCI-Ly3 and OCI-Ly10. In addition ChIP-seq for the TFs IRF4, PU.1 and SPIB from the cell line OCI-LY3 following transfections of scramble/SPIB-siRNA. ChI...
ORGANISM(S): Homo sapiens 
2014-06-03 | E-GEOD-56857 | biostudies-arrayexpress
UnknownA Loop-Mediated Isothermal Amplification (LAMP) Assay Specific to Trichomonas tenax Is Suitable for Use at Point-of-Care.
Not available
S-EPMC8949391 | biostudies-literature
TranscriptomicsInhibition of endogenous MTF-1 signaling in zebrafish embryos identifies novel roles for MTF-1 in development
The MTF-1 transcription factor is considered to be a master regulator of zinc homoestasis. We previously characterized a constitutively nuclear, dominant-negative zebrafish MTF-1/eGFP fusion protein (dnMTF-1). In this study, in vitro transcribed dnMTF-1 mRNA was microinjected into zebrafish embryos ...
ORGANISM(S): Danio rerio 
2014-04-25 | E-GEOD-51298 | biostudies-arrayexpress
UnknownNext-generation sequencing of cerebrospinal fluid for clinical molecular diagnostics in pediatric, adolescent and young adult brain tumor patients.
Not available
S-EPMC9527510 | biostudies-literature
UnknownAssociation of Blood Biomarkers With Acute Sport-Related Concussion in Collegiate Athletes: Findings From the NCAA and Department of Defense CARE Consortium.
Not available
S-EPMC6991302 | biostudies-literature
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