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UnknownTBCRC009: A Multicenter Phase II Clinical Trial of Platinum Monotherapy With Biomarker Assessment in Metastatic Triple-Negative Breast Cancer.
Not available
S-EPMC4451173 | biostudies-literature
ProteomicsA genetic model for in vivo proximity labeling of the mammalian secretome
Yang R, Meyer AS, Droujinine I, Udeshi ND, Hu Y, Guo J, McMahon J, Carey DK, Xu C, Qiao F, Sha J, Qin S, Rocco D, Wohlschlegel J, Ting AY, Carr SA, Perrimon N, McMahon AP. 2022. Organ functions are highly specialized and interdependent. Tissue-specific secreted factors play a critical role in organ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-02-16 | MSV000088848 | MassIVE
TranscriptomicsTranscription profiling of field-caught permethrin-resistant Anopheles gambiae shows over-expression of CYP6P3, a P450 that metabolizes pyrethroids
Field-caught permethrin-resistant Anopheles gambiae s.s. overexpress CYP6P3, a P450 that metabolizes pyrethroids
ORGANISM(S): Anopheles gambiae s.s. 
2009-01-17 | E-MTAB-52 | biostudies-arrayexpress
ProteomicsIn situ cell-surface proteomic profiling in mice
Shuster SA, Li J, Chon U, Hu MC, Luginbuhl DJ, Udeshi ND, Carey DK, Takeo YH, Xu C, Mani D.R., Han S, Ting AY, Carr SA, Luo L. Cell-surface proteins mediate cell-cell interactions throughout the lifetime of multicellular organisms, yet there are no general methods for profiling them in vertebrate t...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-12-03 | MSV000088506 | MassIVE
ProteomicsMolecular basis of TMED9 oligomerization and entrapment of misfolded protein cargo in the early secretory pathway
Xiao L, Pi X, Goss AC, El-Baba T, Ehrmann JF, Grinkevich E, Bazua-Valenti S, Padovano V, Alper SL, Carey D, Udeshi ND, Carr SA, Pablo JL, Robinson CV, Greka A, Wu H. 2024 Intracellular accumulation of misfolded proteins causes serious human proteinopathies. The transmembrane emp24 domain 9 (TMED9) ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-06-29 | MSV000089757 | MassIVE
ProteomicsConstitutively active autophagy dampens inflammation through metabolic and post-transcriptional regulation of macrophage cytokine production
Xu J, Kong L, Oliver B, Li B, Creasey EA, Guzman G, Schenone M, Carey KL, Carr SA, Graham DB, Deguine J, Xavier RJ. 2023. Autophagy is an essential cellular process that is deeply integrated with innate immune signaling; however, studies that examine autophagy in the context of inflammatory conditio...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-06-06 | MSV000092110 | MassIVE
ProteomicsKinome profiling in HER2+ breast cancer patients in response to 7 days of HER2-targeting
Inhibition of the HER2/ERBB2 receptor is a keystone to treating HER2-positive malignancies, particularly breast cancer, but a significant fraction of HER2-positive (HER2+) breast cancers recur or fail to respond. Anti-HER2 monoclonal antibodies, like trastuzumab or pertuzumab, and ATP active site in...
ORGANISM(S): Homo sapiens (Human) 
2021-04-09 | PXD021865 | Pride
Pertuzumab Multiplexed kinase inhibitor beads Trastuzumab Erbb2 Clinical trial Lapatinib 
UnknownSingle cell transcriptomic analysis of HPV16-infected epithelium identifies a keratinocyte subpopulation implicated in cancer.
Not available
S-EPMC10082832 | biostudies-literature
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