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ProteomicsOligodendrocyte precursor cell-specific blocking of low glucose-induced activation of AMPK ensures myelination and remyelination
In this study, we screening the main types of cerebral cortex cells for glucose sensing and have find that AMPK is not activated in OPCs. We further discover that aldolase C (ALDOC) is acetylated at K14 in OPCs. Expression of ALDOC-K14R, with the acetylation lysine residues changed to arginine, rend...
ORGANISM(S): Rattus Rattus Homo Sapiens 
PXD067336 |
TranscriptomicsRNA-seq of two hybrid mouse embryonic stem cell lines in a competitive environment during pluripotency: comparison between separate and co-culture conditions
Compared two hybrid mouse embryonic stem cell lines (that contain the same nuclear background, but different mtDNA content) in separate and co-culture conditions. We investigated the genes differentially expressed between these two cell lines in separate and co-culture as well as the genes that chan...
ORGANISM(S): Mus musculus 
2020-01-18 | E-MTAB-8692 | biostudies-arrayexpress
TranscriptomicsIdentification of novel androgen-regulated pathways and mRNA isoforms through genome-wide exon-specific profiling of the LNCaP transcriptome
Androgens drive the onset and progression of prostate cancer (PCa) by modulating androgen receptor (AR) transcriptional activity. Although several microarray-based studies have identified androgen-regulated genes, here we identify in-parallel global androgen-dependent changes in both gene and alter...
ORGANISM(S): Homo sapiens 
2011-12-27 | E-GEOD-32875 | biostudies-arrayexpress
UnknownAD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation.
Not available
S-EPMC9345574 | biostudies-literature
UnknownMammalian γ2 AMPK regulates intrinsic heart rate.
Not available
S-EPMC5668267 | biostudies-literature
UnknownTop 10 International Priorities for Physical Fitness Research and Surveillance Among Children and Adolescents: A Twin-Panel Delphi Study.
Not available
S-EPMC9399984 | biostudies-literature
UnknownBiomarker-Guided Antibiotic Duration for Hospitalized Patients With Suspected Sepsis: The ADAPT-Sepsis Randomized Clinical Trial.
Not available
S-EPMC11862976 | biostudies-literature
UnknownCost-effectiveness of procalcitonin-guided antibiotic duration for hospitalized patients with sepsis.
Not available
S-EPMC12661845 | biostudies-literature
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