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UnknownMercaptopurine Ingestion Habits, Red Cell Thioguanine Nucleotide Levels, and Relapse Risk in Children With Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group Study AALL03N1.
Not available
S-EPMC5455766 | biostudies-literature
TranscriptomicsAn RNA-Seq Transcriptome Analysis of Pi Deficient White Lupin Reveals Novel Insights Into Phosphorus Acclimation in Plants
Phosphorus, in its orthophosphate form (Pi), is one of the most limiting macronutrients in soils for plant growth and development. However, the whole genome molecular mechanisms contributing to plant acclimation to Pi deficiency remain largely unknown. White lupin (Lupinus albus L.) has evolved uniq...
ORGANISM(S): Lupinus albus 
2012-11-29 | E-GEOD-31132 | biostudies-arrayexpress
TranscriptomicsTCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions
Surprisingly few pathways signal between cells, raising questions about mechanisms for tissue-specific responses. In particular, Wnt ligands signal in many mammalian tissues, including the intestinal epithelium, where constitutive signaling causes cancer. Genome-wide analysis of DNA cis-regulatory r...
ORGANISM(S): Homo sapiens 
2010-08-11 | E-GEOD-22572 | biostudies-arrayexpress
UnknownBaseline Microperimetry and OCT in the RUSH2A Study: Structure-Function Association and Correlation With Disease Severity.
Not available
S-EPMC9712171 | biostudies-literature
GenomicsGenome-wide studies identify a novel interplay between AML1 and AML1/ETO in t(8;21) acute myeloid leukemia
The AML1/ETO fusion protein is essential to the development of acute myeloid leukemia (AML), and is well recognized for its dominant-negative effect on the co-existing wild-type protein AML1. However, the involvement of wild-type AML1 in AML1/ETO-driven leukemogenesis remains elusive. Through chroma...
ORGANISM(S): Homo sapiens 
2015-11-04 | E-GEOD-65427 | biostudies-arrayexpress
UnknownBCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes.
Not available
S-EPMC9414116 | biostudies-literature
GenomicsHistone methylation and transcription factor binding during intestinal cell differentation
Cell differentiation requires epigenetic modulation of tissue-specific genes and activities of master transcriptional regulators, which are recognized for their dominant control over cellular programs. Using novel epigenomic methods, we characterized enhancer elements specifically modified in differ...
ORGANISM(S): Mus musculus 
2010-11-17 | E-GEOD-23436 | biostudies-arrayexpress
TranscriptomicsUsing RNA-Seq for gene identification, polymorphism detection and transcript profiling in two alfalfa genotypes with divergent cell wall composition in stems
Alfalfa, [Medicago sativa (L.) sativa], a widely-grown perennial forage has potential for development as a cellulosic ethanol feedstock. The application of genomic approaches would advance development of alfalfa as a cellulosic feedstock. However, the genomics of alfalfa, a non-model species, is sti...
ORGANISM(S): Medicago sativa 
2011-04-21 | E-GEOD-26757 | biostudies-arrayexpress
UnknownEpidemic spreading model to characterize misfolded proteins propagation in aging and associated neurodegenerative disorders.
Not available
S-EPMC4238950 | biostudies-literature
UnknownCommon variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Not available
S-EPMC3090745 | biostudies-literature
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