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GenomicsMassive genomic rearrangement acquired in a single catastrophic event during cancer development - samples
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
EGAD00001000002 | EGA
GenomicsA Comprehensive Catalogue of Somatic Mutations from a Human Cancer Genome
We have carried out complete sequencing of the genome of the human male maligant melanoma cell line COLO-829 using the Illumina Genome Analyzer II. We generated a sequencing library with a median insert size of ~200 bp following random fragmentation and gel fractionation of the genomic DNA. We seque...
EGAS00000000052 | EGA
GenomicsMassive Genomic Rearrangment Acquired in a Single Catastrophic Event During Cancer Development
Cancer is driven by mutation. Using Agilent exome hybridisation capture and Illumina GA massively parallel sequencing technology, we aim to sequence ~1600 microRNAs plus the protein coding genome of 25 matched human renal cancer samples. Bespoke algorithms are being developed to identify the somatic...
EGAS00000000029 | EGA
TranscriptomicsIn utero exposure to arsenic via drinking water impairs lung development and mucociliary clearance genes.
In utero exposure to arsenic via drinking water increases the risk of lower respiratory tract infections during infancy and mortality from bronchiectasis in adulthood. Pregnant mice were exposed to arsenic, and gene expression patterns were profiled in peripheral lung tissue obtained from the offspr...
ORGANISM(S): Mus musculus 
2013-06-04 | E-GEOD-37831 | biostudies-arrayexpress
UnknownCancer vaccine formulation dictates synergy with CTLA-4 and PD-L1 checkpoint blockade therapy.
Not available
S-EPMC5873868 | biostudies-literature
UnknownGuided by the community: Insights on recruitment science from the African Americans Fighting Alzheimer's in Midlife (AA-FAIM) Project.
Not available
S-EPMC12318541 | biostudies-literature
TranscriptomicsTranscription profiling of human HNSCC survival predictin using FFPE samples
Recently it was shown that gene expression signatures generated from DNA microarray analyses have promise as biomarkers of clinical outcome and that the molecular characteristics of tumors could be elucidated. Through this study, we have determined a high-risk signature for recurrence as a prognosti...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-2837 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human head and neck squamous cell carcinomas that are positive or negative for Human Papilloma Virus
Introduction: Human Papilloma Virus (HPV) is associated with a subset of head and neck squamous cell carcinoma (HNSCC), between 15% and 35% of HNSCC harboring HPV, almost exclusively of subtype 16. Demographic and exposure differences between HPV-positive (+) and negative (-) HNSCCs suggest that HPV...
ORGANISM(S): Homo sapiens 
2007-09-20 | E-GEOD-3292 | biostudies-arrayexpress
GenomicsEGAD00000000055
COLO-829 is a publicly available immortal cancer cell line and COLO-829BL is a lymphoblastoid cell line derived from the same patient
EGAD00000000055 | EGA
UnknownGenetic testing in severe aplastic anemia is required for optimal hematopoietic cell transplant outcomes.
Not available
S-EPMC9412004 | biostudies-literature
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