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TranscriptomicsGenome-wide Expression Assay Comparison Across Frozen and Fixed Postmortem Brain Tissue Samples
Comparison between in vitro transcription- and cDNA-mediated annealing, selection and ligation (DASL)-based assays on brain-specific reference RNA, and postmortem frozen and formalin fixed brain tissue from autistic and control cases. Investigation of data preprocessing techniques for DASL-assayed ...
ORGANISM(S): Homo sapiens 
2012-04-02 | E-GEOD-28475 | biostudies-arrayexpress
TranscriptomicsExpression changes in IC GABA receptors in the auditory midbrain of young adult and aging presbycusis mice.
We performed a microarray analysis of auditory midbrain (inferior colliculus, IC) mRNA from young adult CBA mice (controls) with good hearing, middle aged (MA) with good hearing, and old mild (MP) and severe (SP) presbycusic CBA mice. Fold Change data derived from RMA normalization revealed that the...
ORGANISM(S): Mus musculus 
2013-08-06 | E-GEOD-49522 | biostudies-arrayexpress
TranscriptomicsNovel approach to select genes from RMA normalized microarray data using functional hearing tests in aging mice.
Presbycusis – age-related hearing loss – is the number one communicative disorder of our aged population. Here we analyzed gene expression for a set of GABA receptors in the cochlea of aging CBA mice using the Affymetrix GeneChip MOE430A. Functional phenotypic hearing measures distortion-product oto...
ORGANISM(S): Mus musculus 
2013-08-06 | E-GEOD-49543 | biostudies-arrayexpress
UnknownImpact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines.
Not available
S-EPMC11443006 | biostudies-literature
TranscriptomicsMolecular signatures associated with Mx1-mediated resistance to highly pathogenic influenza virus infection: mechanisms of survival
Understanding the role of host factors during lethal influenza virus infection is critical to deciphering the events that will determine the fate of the host. One such factor is encoded by the Mx1 gene, which confers resistance to influenza virus infection. Here, we compared pathology and global gen...
ORGANISM(S): Mus musculus 
2012-02-20 | E-GEOD-35933 | biostudies-arrayexpress
UnknownInternational severe asthma registry (ISAR): protocol for a global registry.
Not available
S-EPMC7439682 | biostudies-literature
UnknownInterleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19.
Not available
S-EPMC7953461 | biostudies-literature
UnknownExtreme Preterm Infant Rates of Overweight and Obesity at School Age in the SUPPORT Neuroimaging and Neurodevelopmental Outcomes Cohort.
Not available
S-EPMC6109599 | biostudies-literature
UnknownEstimated Global Proportions of Individuals With Persistent Fatigue, Cognitive, and Respiratory Symptom Clusters Following Symptomatic COVID-19 in 2020 and 2021.
Not available
S-EPMC9552043 | biostudies-literature
UnknownElective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.
Not available
S-EPMC8189635 | biostudies-literature
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