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ProteomicsCardiomyocyte Contractile Impairment in Heart Failure Results from Reduced BAG3-mediated Sarcomeric Protein Turnover
The association between reduced myofilament force-generating capacity (Fmax) and heart failure (HF) is clear, however the underlying molecular mechanisms are poorly understood. Here, we show impaired Fmax arises from reduced BAG3-mediated sarcomere turnover. Myofilament BAG3 expression decreases in ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2020-11-06 | MSV000086422 | MassIVE
UnknownDecreased free d-aspartate levels are linked to enhanced d-aspartate oxidase activity in the dorsolateral prefrontal cortex of schizophrenia patients.
Not available
S-EPMC5441530 | biostudies-literature
UnknownCausal Deep CASA for Monaural Talker-Independent Speaker Separation.
Not available
S-EPMC7654633 | biostudies-literature
UnknownDNA methylation landscape of the genes regulating D-serine and D-aspartate metabolism in post-mortem brain from controls and subjects with schizophrenia.
Not available
S-EPMC6033866 | biostudies-literature
UnknownThe COVID-19 Assessment for Survival at Admission (CASA) Index: A 12 Months Observational Study.
Not available
S-EPMC8514624 | biostudies-literature
GenomicsSequence Requirements for Cascade Function in a Type I-E CRISPR System: ChIP Library-seq
We generated a collection of 13 plasmids, with each plasmid containing a variant of a CRISPR protospacer targeted by spacer 8 of the E. coli CRISPR-I array. We transformed the plasmids as a pool into delta cas3 E. coli cells expressing all other cas genes constitutively, with FLAG-tagged casA. We th...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2017-08-24 | E-MTAB-5972 | biostudies-arrayexpress
UnknownThe Emerging Role of Altered d-Aspartate Metabolism in Schizophrenia: New Insights From Preclinical Models and Human Studies.
Not available
S-EPMC6232865 | biostudies-literature
UnknownFree D-aspartate regulates neuronal dendritic morphology, synaptic plasticity, gray matter volume and brain activity in mammals.
Not available
S-EPMC4119226 | biostudies-literature
UnknownSelective demethylation of two CpG sites causes postnatal activation of the Dao gene and consequent removal of D-serine within the mouse cerebellum.
Not available
S-EPMC6819446 | biostudies-literature
UnknownD-dimer and reduced-dose apixaban for extended treatment after unprovoked venous thromboembolism: the Apidulcis study.
Not available
S-EPMC9691910 | biostudies-literature
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