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TranscriptomicsTranscription profiling of Xenopus laevis early embryos to investigate the roles of Nodal, Mixer and Sox17 in endoderm formation
A conserved molecular pathway has emerged controlling endoderm formation in Xenopus zebrafish and mice. Key genes in this pathway include Nodal ligands and transcription factors of the Mix-like paired homeodomain class, Gata4-6 zinc finger factors and Sox17 HMG domain proteins. While a linear epista...
ORGANISM(S): Xenopus laevis 
2007-10-05 | E-GEOD-4448 | biostudies-arrayexpress
MetabolomicsLipid mediators of inflammation in BALF 6-19 days after infection with influenza
In this study broncho-alveolar lavage fluid (BALF) from mice infected with influenza A virus, PR8 (280 PFU) was analyzed for lipidomic host response in comparison with the mock infected animals. Time Points: 6, 9, 11, 13 and 19 days post infection, done in 8-10 replicates.)
2013-05-30 | MTBLS32 | MetaboLights
MetabolomicsLipid mediators of inflammation in BALF 3-13 days after infection with influenza
In this study broncho-alveolar lavage fluid (BALF) from mice infected with influenza A virus, PR8 (200 PFU) or X31 (200,000 PFU) was analyzed for lipidomic host response in comparison with the mock infected animals. Time Points: 3, 5, 6, 7, 9, 10 and 13 days post infection.)
2013-05-30 | MTBLS34 | MetaboLights
MetabolomicsLipid mediators of inflammation in BALF 3-19 days after infection with influenza
In this study broncho-alveolar lavage fluid (BALF) from mice infected with influenza A virus, PR8 (200 PFU and 200,000 PFU), X31 (2000,000 PFU) was analyzed for lipidomic host response in comparison with the mock infected animals. Time Points: 3, 5, 7, 9, 11, 13, 19 days post infection, done in 8-10...
2013-05-09 | MTBLS31 | MetaboLights
GenomicsFoxp3 exploits a preexistent enhancer landscape for regulatory T cell lineage specification
This SuperSeries is composed of the following subset Series: GSE40684: Foxp3 exploits a preexistent enhancer landscape for regulatory T cell lineage specification [ChIP-Seq] GSE40685: Foxp3 exploits a preexistent enhancer landscape for regulatory T cell lineage specification [Expression] Refer to in...
ORGANISM(S): Mus musculus 
2012-09-28 | E-GEOD-40686 | biostudies-arrayexpress
ProteomicsIdentification of enriched O-GlcNAc proteins in hypertrophic mouse hearts
We used C57/Bl6 mice subjected to sham or transverse aortic constriction (TAC) to create pressure-overload hypertrophy (POH). From the hearts, we stabilized and labelled the O-GlcNAc moiety with tetramethylrhodamine azide (TAMRA) before enriching by TAMRA immunoprecipitation (files with "TAMRAIP"). ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-02-07 | MSV000088797 | MassIVE
ProteomicsIdentification of enriched O-GlcNAc proteins in hypertrophic and normal mouse hearts
Bottom up proteomics of O-GlcNAc antibody enriched proteins from mouse heart tissue (hypertrophic vs. normal). O-GlcNAc proteins were labeled with a click chemistry kit with the tetramethylrhodamine (TAMRA) tag, then the labeled proteins were enriched with TAMRA antibody for proteomics experiments.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-12-06 | MSV000088525 | MassIVE
TranscriptomicsFoxp3 exploits a preexistent enhancer landscape for regulatory T cell lineage specification [Expression]
Regulatory T (Treg) cells, whose identity and function are defined by the transcription factor Foxp3, are indispensable for immune homeostasis. It is unclear whether Foxp3 exerts its Treg lineage specification function through active modification of the chromatin landscape and establishment of new ...
ORGANISM(S): Mus musculus 
2012-09-28 | E-GEOD-40685 | biostudies-arrayexpress
GenomicsFoxp3 exploits a preexistent enhancer landscape for regulatory T cell lineage specification [ChIP-Seq]
Regulatory T (Treg) cells, whose identity and function are defined by the transcription factor Foxp3, are indispensable for immune homeostasis. It is unclear whether Foxp3 exerts its Treg lineage specification function through active modification of the chromatin landscape and establishment of new ...
ORGANISM(S): Mus musculus 
2012-09-28 | E-GEOD-40684 | biostudies-arrayexpress
GenomicsGenomic DNA in Normal and Cancerous Prostate Cells
To investiagate copy number differences between PrEC and LNCaP cells, each was DNA sequenced. One PrEC sample, a normal cell line. One LNCaP sample, a cancer cell line.
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-38674 | biostudies-arrayexpress
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