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TranscriptomicsMC70 potentiates doxorubicin efficacy in colon and breast cancer in vitro treatment
A major limitation in the cancer treatment is the ability of cancer cells to become resistant to chemotherapeutic drugs, by multidrug establishment. Here, we evaluate the possibility to utilize MC70, either as ABC transporters inhibitor or as anticancer agent, in monotherapy or in combination with d...
ORGANISM(S): Homo sapiens 
2010-12-22 | E-GEOD-26250 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression profiles of effector T cells from leptin-receptor-deficient mice and wild type mice
We have employed whole genome microarray expression profiling as a discovery platform to identify genes differentially expressed during leptin receptor deficiency, which is partly responsible for the inhibition of T cell effector functions. Mouse CD4+CD25- T cells were purified from leptin-receptor-...
ORGANISM(S): Mus musculus 
2012-09-05 | E-GEOD-29607 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of effector T cells induced by mTOR inhibition
To further develop our gene expression approach to treatment of autoimmunity, we have employed whole genome microarray expression profiling as a discovery platform to identify genes differentially expressed upon immunosuppressor treatment responsible for inhibition of T cell effector functions. Huma...
ORGANISM(S): Homo sapiens 
2012-09-05 | E-GEOD-29606 | biostudies-arrayexpress
UnknownLongitudinal analysis of the gut microbiota during anti-PD-1 therapy reveals stable microbial features of response in melanoma patients.
Not available
S-EPMC11629153 | biostudies-literature
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