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TranscriptomicsTime-course effect of APRIL on gene expression in HepG2 cells
APRIL (TNFSF13) is a ligand of the TNF superfamily which binds to two receptors, BCMA and TACI. We have found that APRIL and its receptor BCMA are specifically enhanced in hepatocellular carcinoma, as compared to non-cancerous liver tissue. We further identified that HepG2 cells present the same lig...
ORGANISM(S): Homo sapiens 
2011-05-20 | E-GEOD-29375 | biostudies-arrayexpress
TranscriptomicsTime-course effect of estradiol and ERa17p on Early Gene expression in T47D cells
ERM-NM-117p is a synthetic peptide corresponding to the sequence P295LMIKRSKKNSLALSLT311 of the estrogen receptor alpha (ERM-NM-1) and initially synthesized to mimic its calmodulin binding site. ERM-NM-117p was subsequently found to elicit estrogenic responses in E2-deprived ERM-NM-1-positive breast...
ORGANISM(S): Homo sapiens 
2012-07-30 | E-GEOD-39720 | biostudies-arrayexpress
TranscriptomicsTime-course effect of estradiol and ERa17p on Early Gene expression in MDA-MB-231 cells
ERM-NM-117p is a synthetic peptide corresponding to the sequence P295LMIKRSKKNSLALSLT311 of the estrogen receptor alpha (ERM-NM-1) and initially synthesized to mimic its calmodulin binding site. ERM-NM-117p was subsequently found to elicit estrogenic responses in E2-deprived ERM-NM-1-positive breast...
ORGANISM(S): Homo sapiens 
2012-07-30 | E-GEOD-39718 | biostudies-arrayexpress
TranscriptomicsTime-course effect of estradiol and ERa17p on Early Gene expression in SKBR3 cells
ERM-NM-117p is a synthetic peptide corresponding to the sequence P295LMIKRSKKNSLALSLT311 of the estrogen receptor alpha (ERM-NM-1) and initially synthesized to mimic its calmodulin binding site. ERM-NM-117p was subsequently found to elicit estrogenic responses in E2-deprived ERM-NM-1-positive breast...
ORGANISM(S): Homo sapiens 
2012-07-30 | E-GEOD-39719 | biostudies-arrayexpress
TranscriptomicsEffect of tamoxifen on early gene expression in T47D cells
Tamoxifen is the treatment of choice in estrogen receptor alpha breast cancer patients. However, ~50% of ERM-NM-1-positive tumors exhibit intrinsic or rapidly acquire resistance to endocrine treatment, requiring chemotherapy. M-NM-^Yt has been difficult to predict de novo resistance to endocrine the...
ORGANISM(S): Homo sapiens 
2014-08-29 | E-GEOD-60878 | biostudies-arrayexpress
TranscriptomicsTime-course effect of estradiol and estradiol-BSA on early gene expression in SKBR3 cells
Estrogens have been reported to activate several processes via membrane binding to either classic estrogen receptors (ERs) or GPR30. We have used either estradiol or BSA-conjugated estradiol in order to initiate membrane-initiated actions and ICI 172,780 (ICI) or G15 to explore ER- and GPR30-related...
ORGANISM(S): Homo sapiens 
2012-01-01 | E-GEOD-32669 | biostudies-arrayexpress
TranscriptomicsTime-course effect of estradiol and estradiol-BSA on early gene expression in T47D cells
Estrogens have been reported to activate several processes via membrane binding to either classic estrogen receptors (ERs) or GPR30. We have used either estradiol or BSA-conjugated estradiol in order to initiate membrane-initiated actions and ICI 172,780 (ICI) or G15 to explore ER- and GPR30-related...
ORGANISM(S): Homo sapiens 
2012-01-01 | E-GEOD-32666 | biostudies-arrayexpress
TranscriptomicsEffect of tamoxifen on early gene expression in MDA-MB-231 cells
Tamoxifen is the treatment of choice in estrogen receptor alpha breast cancer patients. However, ~50% of ERM-NM-1-positive tumors exhibit intrinsic or rapidly acquire resistance to endocrine treatment, requiring chemotherapy. M-NM-^Yt has been difficult to predict de novo resistance to endocrine the...
ORGANISM(S): Homo sapiens 
2014-08-29 | E-GEOD-60879 | biostudies-arrayexpress
TranscriptomicsTime-course effect of estradiol and estradiol-BSA on early gene expression in MCF-7 cells
Estrogens have been reported to activate several processes via membrane binding to either classic estrogen receptors (ERs) or GPR30. We have used either estradiol or BSA-conjugated estradiol in order to initiate membrane-initiated actions and ICI 172,780 (ICI) or G15 to explore ER- and GPR30-related...
ORGANISM(S): Homo sapiens 
2012-01-01 | E-GEOD-32667 | biostudies-arrayexpress
TranscriptomicsTime-course effect of estradiol and estradiol-BSA on early gene expression in MDA-MB-231 cells
Estrogens have been reported to activate several processes via membrane binding to either classic estrogen receptors (ERs) or GPR30. We have used either estradiol or BSA-conjugated estradiol in order to initiate membrane-initiated actions and ICI 172,780 (ICI) or G15 to explore ER- and GPR30-related...
ORGANISM(S): Homo sapiens 
2012-01-01 | E-GEOD-32668 | biostudies-arrayexpress
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