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TranscriptomicsmiRNA profiling from freshly harvested duodenums and livers
This SuperSeries is composed of the following subset Series: GSE18774: miRNA profiling from freshly harvested duodenums GSE18775: miRNA profiling from freshly harvested livers Refer to individual Series
ORGANISM(S): Mus musculus 
2010-06-20 | E-GEOD-18788 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling from freshly harvested duodenums
Correlation of miRNA expression patterns with clinically relevant information is greatly facilitated by the retrospective analysis of samples archived in tissue banks. Unfortunately, the quality of samples stored in tissue banks is variable due to heterogeneity in pre-analytical preparation of clini...
ORGANISM(S): Mus musculus 
2010-06-20 | E-GEOD-18774 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling from freshly harvested livers
Correlation of miRNA expression patterns with clinically relevant information is greatly facilitated by the retrospective analysis of samples archived in tissue banks. Unfortunately, the quality of samples stored in tissue banks is variable due to heterogeneity in pre-analytical preparation of clini...
ORGANISM(S): Mus musculus 
2010-06-20 | E-GEOD-18775 | biostudies-arrayexpress
TranscriptomicsEvaluation of the effect of antimiR-122 administration on the liver, spleen and heart miRNome
To determine the effect of antimiR-122 administration on the mouse miRNome. To functionally investigate a possible link between miR-122 and iron metabolism we inhibited miR-122 by a single, intraperitoneal injection of Locked Nucleic Acid (LNA)-modified antimiR oligonucleotides into age- and sex-mat...
ORGANISM(S): Mus musculus 
2010-10-20 | E-GEOD-24786 | biostudies-arrayexpress
TranscriptomicsmiRNA degradation in frozen tissue
To determine the effect of RNA degradation on miRNA expression profiling. To mimic total RNA degradation in snap-frozen livers and duodenums from mice (wild type female, C57/Bl6) tissues were stored in a -80°C freezer and then transferred to dry ice. Each frozen tissue was sliced into five identica...
ORGANISM(S): Mus musculus 
2010-05-19 | E-GEOD-19104 | biostudies-arrayexpress
TranscriptomicsMYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma.
MYCN is a master regulator controlling many processes necessary for tumor cell survival. Here, we unravel a microRNA network that causes tumor suppressive effects in MYCN-amplified neuroblastoma cells. In profiling studies, histone deacetylase (HDAC) inhibitor treatment most strongly induced miR-183...
ORGANISM(S): Homo sapiens 
2013-05-01 | E-GEOD-44538 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human mesenchymal stem cells to determine changes over the course of cellular aging
To determine gene expression changes during in vitro senescence of MSC we have analyzed differential expression of the corresponding early passage (P2) and senescent passage (PX). There were global changes in the gene expression profile that were reproducible in three independent donor samples. Expe...
ORGANISM(S): Homo sapiens 
2008-10-20 | E-GEOD-9593 | biostudies-arrayexpress
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