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MetabolomicsCars2-Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2.
Targeting transcriptional regulatory complexes represents a promising strategy for activating thermogenic fat and treating obesity. In this study, we focused on identifying critical, specific metabolic pathways enriched during brown adipocyte differentiation. Through analysis of metabolomics and RNA...
2026-03-24 | MTBLS12237 | MetaboLights
MetabolomicsHyaluronan catabolism supports the peritoneal disseminated metastasis of cancer through the glucuronic acid pathway
When disseminated into the peritoneal cavity at the very early stage, cancer cells must adapt to the glucose- and oxygen-limited environment in peritoneal fluid, yet the key molecular regulators remain undefined. Here, we reveal that early disseminated OC cells are ingeniously utilize hyaluronic aci...
2026-07-10 | MTBLS15007 | MetaboLights
MetabolomicsBacteria encode their own post-mortem protein catabolism to enable nutrient recycling
For many organisms, death is a tangible, visible event. In bacteria, death can be a natural or an induced process 1. Death permits genes conferring a survival advantage to be selected in a bacterial population. Furthermore, biomolecule recycling from dead bacteria is crucial under nutrient limitatio...
2025-01-23 | MTBLS10044 | MetaboLights
MetabolomicsCarS2-mediated cysteine catabolism drives brown fat development and thermogenesis through persulfidating EBF2
Targeting transcriptional regulatory complexes is a promising strategy to activate thermogenic fat and treat obesity. In this study, we focused on identifying critical and specific metabolic pathways enriched during brown adipocyte differentiation. By analyzing metabolomics and RNA sequencing result...
2026-03-24 | MTBLS12234 | MetaboLights
MetabolomicsCatabolism of branched-chain amino acids (BCAAs) in renal cells HK2 and 786-O
Not available
ORGANISM(S): Homo sapiens 
ST002220 | MetabolomicsWorkbench
MetabolomicsChemoresistant Cancer Cell Lines are Characterized by Migratory, Amino Acid Metabolism, Protein Catabolism and IFN1 Signalling Perturbations
Not available
ORGANISM(S): Homo sapiens 
ST002104 | MetabolomicsWorkbench
ProteomicsOptimization of a heterologous pathway for protocatechuate catabolism in Escherichia coli
Optimization of a heterologous pathway for protocatechuate catabolism in Escherichia coli
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2017-05-30 | MSV000081122 | MassIVE
MetabolomicsPiperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages.
Not available
ORGANISM(S): Plasmodium falciparum 
ST002181 | MetabolomicsWorkbench
MetabolomicsTime sensitive contribution of the BCAA catabolism to the TCA cycle carbons in HK2, 786-O, OS-RC-2 and RFX-631
Not available
ORGANISM(S): Homo sapiens 
ST002225 | MetabolomicsWorkbench
MetabolomicsHepatic Phosphatidylcholine Catabolism Driven by PNPLA7 and PNPLA8 Supplies Endogenous Choline to Replenish the Methionine Cycle with Methyl Groups (Pnpla7-knockout)
Not available
ORGANISM(S): Mus musculus 
ST002377 | MetabolomicsWorkbench
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