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MetabolomicsSeipin Governs Caveolin-1 Trafficking Through Modulating Sphingolipid-Glycerolipid Balance

Dysregulation of Caveolin-1 (CAV1), a key component of caveolae, leads to pleiotropic disorders; yet, the mechanisms controlling its trafficking remain unclear. Here, we show that the lipid droplet (LD) biogenesis factor seipin controls CAV1 localization. Seipin deficiency in mice and HeLa cells ...

2025-07-22 | MTBLS12759 | MetaboLights
ProteomicsQuantitative proteomic Analysis Reveals up-regulation of caveolin-1 in FOXP3-overexpressed human gastric cancer cells
Forkhead box protein 3 (FOXP3) is implicated in tumor progression and prognosis in various types of tumor cells. We have recently reported that FOXP3 inhibited proliferation of gastric cancer (GC) cells through activating the apoptotic signaling pathway. In this study, we found that over-expression ...
ORGANISM(S): Homo sapiens (Human) 
2017-11-03 | PXD007725 | Pride
Foxp3  cav1  gastric cancer  label-free proteomic analysis 
UnknownCAV1 and KRT5 are potential targets for prostate cancer.
Not available
S-EPMC10713156 | biostudies-literature
UnknownPrognostic Value of CAV1 and CAV2 in Head and Neck Squamous Cell Carcinoma.
Not available
S-EPMC9952890 | biostudies-literature
UnknownIdentification of CAV1 and CDH5 as potential diagnostic and prognostic biomarkers in lung adenocarcinoma.
Not available
S-EPMC12569745 | biostudies-literature
ProteomicsQuantitative proteomic Analysis Reveals up-regulation of caveolin-1 inFOXP3-overexpressed human gastric cancer cells
Forkhead box protein 3 (FOXP3) is associated with tumor progression and prognosis in various types of tumor cells. We have recently reported that FOXP3 inhibited proliferation of gastric cancer (GC) cells through activating the apoptotic signaling pathway. In this study, we found that over-expressio...
ORGANISM(S): Homo Sapiens 
PXD054940 |
UnknownmiRNA-target network reveals miR-124as a key miRNA contributing to clear cell renal cell carcinoma aggressive behaviour by targeting CAV1 and FLOT1.
Not available
S-EPMC4494957 | biostudies-literature
UnknownHOTAIR/miR-203/CAV1 Crosstalk Influences Proliferation, Migration, and Invasion in the Breast Cancer Cell.
Not available
S-EPMC9569926 | biostudies-literature
TranscriptomicsDifferential Gene Expression in Granulosa Cells from Polycystic Ovary Syndrome Patients with and without Insulin Resistance: Identification of Susceptibility Gene Sets through Network Analysis
Polycystic ovary Syndrome (PCOS) is a heterogeneous endocrine disorder that shows evidence of genetic predidposition among affected individuals. We have utilized the Microarray data from granulosa cells of normal and PCOS women for network construction. Human granulosa cells were isolated from ovar...
ORGANISM(S): Homo sapiens 
2012-11-06 | E-GEOD-34526 | biostudies-arrayexpress
ProteomicsSingle-Cell and Proteomic Profiling Identify Cav-1β Expression during Human Plasma Cell Differentiation and Its Association with the V-ATPase–RAGulator–RAG Complex
Human B cell differentiation into memory B cells and antibody-secreting plasma cells (PCs) involves coordinated transcriptional and cellular remodeling. Using an optimized in vitro differentiation system combined with single-cell transcriptomics, we reconstructed human B cell differentiation traject...
ORGANISM(S): Homo sapiens (Human) 
2026-09-18 | PXD079880 | Pride
Secretory machinery of pcs Mtorc signaling Cav1 network Er remodeling program 
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