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We used oligonucleotide microarrays to find differentially expressed genes between control subjects and those affected by sporadic amyotrophic lateral sclerosis. Experiment Overall Design: Complementary RNAs (cRNAs) labelled with Cy5-CTP (Perkin-Elmer) were synthesized from 1 µg of total RNA of eac...
ORGANISM(S): Homo sapiens 
Primary cultures of Cerebellar Granule Neurons (CGNs) have been extensively utilized to examine the signal transduction mechanisms underlying neuronal apoptosis. We conducted whole-genome expression profiling to decipher the transcriptional program controlling the apoptotic/survival switch in cerebe...
ORGANISM(S): Rattus norvegicus 
We performed gene expression profiles of spinal cord samples of ALS patients (30) and controls (10) in order to obtain transcriptomics information belonging to different brain regions of ALS patients. Motor cortex gene expression profiles of the same patients were previously submitted (E-MTAB-2325) ...
ORGANISM(S): Homo sapiens 
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