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Calcific aortic valve disease (CAVD) is an slowly progressive calcification of heart valve which leads to aortic stenosis. The only existing treatment of CAVD is surgical replacment of calcified valve - development of anti-CAVD treatment is urgent task. For better understanding of molecular mechanis...
ORGANISM(S): Homo sapiens (Human) 
2022-10-21 | PXD032212 | Pride
Microbiota exploring in CAVD: the potential fil rouge from aortic valve calcification to infiltrating bacteria
Calcific aortic valvular disease (CAVD) is characterized by sclerosis of the aortic valve leaflets and recent clinical studies have linked several other risk factors to this disease, including male sex. In this study we examined potential sex-related differences in gene expression profiles between ...
ORGANISM(S): Sus scrofa 
This study aimed to define changes in the metabolic and protein profiles of patients with calcific aortic valve disease (CAVD).
ORGANISM(S): Homo Sapiens 
2022-09-19 | PXD036839 |
Genomics
Gut Microbially Produced Butyric Acid Impedes CAVD Pathogenesis by Mediates Competitive Modification of Lactylation and Butyrylation
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