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UnknowncBAF complex components and MYC cooperate early in CD8+ T cell fate.
Not available
S-EPMC9623036 | biostudies-literature
UnknownA disordered region controls cBAF activity via condensation and partner recruitment.
Not available
S-EPMC10792396 | biostudies-literature
UnknownEfficacy of CBP/p300 Dual Inhibitors against Derepression of KREMEN2 in cBAF-Deficient Cancers.
Not available
S-EPMC11701801 | biostudies-literature
UnknownTargeting SUMOylation promotes cBAF complex stabilization and disruption of the SS18::SSX transcriptome in synovial sarcoma.
Not available
S-EPMC12589557 | biostudies-literature
ProteomicsTargeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in Synovial Sarcoma
Synovial Sarcoma (SS) is driven by the SS18::SSX fusion oncoprotein and is ultimately refractory to therapeutic approaches. SS18::SSX alters ATP-dependent chromatin remodeling BAF (mammalian SWI/SNF) complexes, leading to the degradation of canonical (cBAF) complex and amplified presence of an SS18:...
ORGANISM(S): Homo sapiens (Human) 
2025-08-07 | PXD059936 | Pride
Synovial sarcoma  baf complexes  swi/snf  sumoylation  tak-981  subasumstat  dna damage  targeted therapy 
UnknownCo-condensation between transcription factor and cBAF selectively modulates chromatin remodeling and gene expression.
Not available
S-EPMC12819386 | biostudies-literature
UnknownDifferential modulation of polycomb-associated histone marks by cBAF, pBAF, and gBAF complexes.
Not available
S-EPMC11361369 | biostudies-literature
UnknownSynovial sarcoma reprograms transcription by GBAF activation of polycomb targets and loss of CBAF enhancers.
Not available
S-EPMC12852873 | biostudies-literature
ProteomicsPBAF/cBAF reorganization on H3.3 chromatin regulates BMAL1 activity in the absence of circadian negative feedback.
Circadian rhythms in gene expression are coincident with 24hr dynamics in the recruitment of the core-clock transcription factor heterodimer CLOCK-BMAL1 to chromatin. In the liver, circadian chromatin is characterized by rhythmic histone modifications and the deposition of histone variant H2A.Z. How...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-22 | PXD061974 | Pride
Chromatin remodelers Circadian clocks Chromatin dynamics H3.3a histone variant 
UnknownTargeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in Synovial Sarcoma.
Not available
S-EPMC11177989 | biostudies-literature
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