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GenomicsCCR8 expression defines tissue-resident memory T cells in human skin
CCR8 expression defines tissue-resident memory T cells in human skin
PRJEB24073 | ENA
TranscriptomicsCCR8 expression defines tissue-resident memory T cells in human skin
Human skin harbors two major T cell compartments of equal size that are distinguished by expression of the chemokine receptor CCR8. In vitro studies have demonstrated that CCR8 expression is under strict control of T cell antigen receptor (TCR)-engagement and the skin tissue microenvironment. We her...
ORGANISM(S): Homo sapiens 
2017-12-11 | E-MTAB-6370 | biostudies-arrayexpress
GenomicsCCR8+ decidual regulatory T cells maintain maternal-fetal immune tolerance during early pregnancy
CCR8+ decidual regulatory T cells maintain maternal-fetal immune tolerance during early pregnancy
PRJNA1058460 | ENA
UnknownIdentification of human CCR8 as a CCL18 receptor.
Not available
S-EPMC3782048 | biostudies-literature
TranscriptomicsCCR8+ decidual regulatory T cells maintain maternal-fetal immune tolerance during early pregnancy
Regulatory T cells (Tregs) play crucial roles in maintaining maternal immune tolerance to the semi-allogeneic fetus during pregnancy, but Treg population heterogeneity and tissue-specific functions in human decidua remain largely unknown. Here, we conducted single-cell transcriptomic and T cell rece...
ORGANISM(S): Homo sapiens 
2025-04-15 | GSE252187 | GEO
UnknownS-531011, a Novel Anti-Human CCR8 Antibody, Induces Potent Antitumor Responses through Depletion of Tumor-Infiltrating CCR8-Expressing Regulatory T Cells.
Not available
S-EPMC10477828 | biostudies-literature
UnknownCCR8 Expression Defines Tissue-Resident Memory T Cells in Human Skin.
Not available
S-EPMC5818732 | biostudies-literature
UnknownCC chemokine CCL1 receptor CCR8 mediates conversion of mesenchymal stem cells to embryoid bodies expressing FOXP3+CCR8+ regulatory T cells.
Not available
S-EPMC6636727 | biostudies-literature
GenomicsType I interferon limits ILC2 effector functions through suppression of the CCR8-CCL1/CCL8 axis
Type I interferon limits ILC2 effector functions through suppression of the CCR8-CCL1/CCL8 axis
PRJNA746475 | ENA
UnknownDifferential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibody.
Not available
S-EPMC9639568 | biostudies-literature
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