Cd22 - OmicsDI

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[3-Methyl-1-[3-methyl-1-oxo-1-(2,3,4,5,6-pentahydroxyhexoxy)pentan-2-yl]oxy-1-oxobutan-2-yl] 2-hydroxy-3-methylpentanoate (1)
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bacteria (1)

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Transcription profiling by array (17)
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Lab affiliation

Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany (3)
Assistant Professor, Pediatrics-Heme/Onc and Bone Marrow Transplantation (1)
Immunology Department, Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland (1)
Department of Obstetrics, Gynecology, and Reproductive Sciences, Center for Reproductive Sciences, University of California, San Francisco, CA 94143, USA Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA Department of Anatomy, University of California, San Francisco, CA 94143, USA (1)
Department of Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology and Signalling Research Centres BIOSS and CIBSS, University of Freiburg, 79104 Freiburg im Breisgau, Germany (1)
Academia Sinica, Institute of Biological Chemistry (1)
Bioanalytical Mass Spectrometry Group, Max Planck Institute for Multidisciplinary Sciences, 37077 Göttingen, Germany. (1)
Lymphoid Malignancies Branch Center for Cancer Research National Cancer Institute National Institutes of Health Bethesda, Maryland (1)

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CD22 interactome

CD22 (Siglec-2) is a member of the Siglec family. It is an inhibitory co-receptor of the B-cell-receptor (BCR) and inhibits B–cell activation. Upon BCR stimulation ITIMs in the cytoplasmic tail of CD22 are phosphorylated. This triggers CD22 signalling pathways, which lead to a decreased calcium mobi...

ORGANISM(S): Gallus gallus (Chicken)

2020-05-06 | PXD013801 | Pride

Cullin 3 Silac B cells Cd22 Qexactive plus Dt40 cells

CD22 Blockade Alleviates Anesthesia Surgery-Mediated Cognitive Impairment in Aged Mice

Postoperative cognitive dysfunction (POCD) is a common complication characterized by cognitive decline following surgery, with neuroinflammation serving as a critical pathogenic mechanism. Emerging evidence indicates that CD22, an inhibitory receptor primarily expressed on B cells and microglia, ...

2025-09-24 | MTBLS13028 | MetaboLights

Sphingomonas sp. CD22

Sphingomonas sp. CD22 Genome sequencing and assembly

PRJNA1037727 | ENA

Clostridioides difficile CD22

Clostridioides difficile CD22 Genome sequencing and assembly

PRJNA85691 | ENA

Identification of transcription factors regulating CD22 transcription

CD22 (also known as Siglec-2) belongs to the Siglec family of glycan-recognition proteins and negatively regulates B-cell receptor-mediated signaling. CD22 protein is known to be down-regulated in the B cells of patients with chronic lymphocytic leukemia (CLL). However, the mechanism regulating the ...

ORGANISM(S): Homo sapiens (Human)

2025-03-26 | PXD054553 | Pride

Transcription factor B lymphocytes Burkitt lymphoma Minimal promoter Dna pull down-proteomics Cd22 Chronic lymphocytic leukemia

CD22 modulation regulates neuroinflammation in microglia

PRJNA1120353 | ENA

Gene expression profiles of ALL cells

Using using ATLAS cDNA expression arrays, we performed gene expression profiling of primary leukemia cells from 31 infants and 30 non-infant children (pediatric patients) with ALL to determine if any of these signature genes are differentially expressed in infant ALL vs. pediatric ALL. Reduced expr...

ORGANISM(S): Homo sapiens

2010-09-10 | E-GEOD-24000 | biostudies-arrayexpress

Transcriptional responses of T cells activated via CD22-specific T cell receptor compared to CD22-specific chimeric antigen receptor

PRJNA1074674 | ENA

scRNA sequencing analysis of CD22(-) CD4+ T cells during viral infection

PRJEB101105 | ENA

CD22 blockage restores age-related impairments of microglia surveillance capacity

PRJNA715777 | ENA

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