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ModelsWodarz1999 CTL memory response HIV
This a model from the article: Specific therapy regimes could lead to long-term immunological control of HIV. Wodarz D, Nowak MA. Proc Natl Acad Sci U S A 1999 Dec 7;96(25):14464-9 10588728 , Abstract: We...
2024-09-02 | BIOMD0000000683 | BioModels
TranscriptomicsSingle-cell multiome analysis of human in vitro activated CD4 T cells
This study looks at the ATAC+RNA profiles of human CD4 T cells under bioreactor-like conditions as ACT. Cells were stimulated toward Th1,Th2,Treg and Th17 under anti-CD3/28 activation, and profiled on day 5.
ORGANISM(S): Homo sapiens 
2024-01-31 | E-MTAB-13711 | biostudies-arrayexpress
ModelsWodarz2007 - HIV/CD4 T-cell interaction
Wodarz2007 - HIV/CD4 T-cell interaction A deterministic model illustrating how CD4 T-cells can influence HIV infection. This model is described in the article: Infection dynamics in HIV-specific CD4 T cells: does a CD4 T cell boost benefit the ...
2024-09-02 | BIOMD0000000663 | BioModels
TranscriptomicsTranscriptome and Molecular Pathways Analysis of CD4 T-Cells from Young NOD Mice
Type 1 diabetes is a multigenic disease caused by T-cell mediated destruction of the insulin producing β-cells. Although conventional (targeted) approaches of identifying causative genes have advanced our knowledge of this disease, many questions remain unanswered. Using a whole molecular systems st...
ORGANISM(S): Mus musculus 
2014-06-20 | E-GEOD-46600 | biostudies-arrayexpress
GenomicsComparison of transcriptome between E8I knock-out and wild type mouse during CD4 CTL polarization in vitro
Comparison of transcriptome between E8I knock-out and wild type mouse during CD4 CTL polarization in vitro
PRJNA454579 | ENA
ProteomicsA multi-target molecule restores immune response in lung cancer through intratumoral CD4+ cytotoxic lymphocytes recruitment
Background: Despite current therapeutic treatments including surgery, chemotherapy, radiotherapy and recently immunotherapy, the mortality rate of lung cancer stays high. Regarding lung cancer, epigenetic modifications altering cell cycle, angiogenesis and programmed cancer cell death are therapeut...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-16 | PXD042991 | Pride
Moa Expression proteomics Mass spectrometry Cd4 ctl Drug targets Mhc-ii Pisa assay Lung cancer Hdac6 
TranscriptomicsGene expression profiling of human Th17 cell differentiation
The study aims at identifying transcriptional changes induced by in vitro polarization of human cord blood CD4+ cells towards Th17 subtype with combination of IL6, IL1b and TGFb by using timeseries data. In this study, we identified gene expression changes characterizing early stages of human Th17 c...
ORGANISM(S): Homo sapiens 
2012-05-03 | E-GEOD-35103 | biostudies-arrayexpress
UnknownConditions for the generation of cytotoxic CD4(+) Th cells that enhance CD8(+) CTL-mediated tumor regression.
Not available
S-EPMC5007627 | biostudies-literature
GenomicsCD4 CTL RNA-seq
Single-cell RNA sequencing of CD4 T cells 7 days after infection or immunisation
PRJEB14043 | ENA
GenomicsSTAT1 and STAT3 ChIP-seq for naive and effector memory (Tem) CD4 T-cells after IL-6 treatment
Naïve and activated T-cells has a different response to antigenic challenge. We examine whether a cytokine like IL-6 induces different responses through the Jak-STAT pathway to affect the functional characteristics of a given CD4 T‑cell subset. We isolated naïve and effector memory (Tem) CD4 T-cells...
ORGANISM(S): Mus musculus 
2019-02-08 | E-MTAB-6273 | biostudies-arrayexpress
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