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The effect of cdc5-1 on small RNA accumulation
In budding yeast, the Mitotic Exit Network (MEN), a GTPase signaling cascade integrates spatial and temporal signals to promote exit from mitosis. This signal integration requires transmission of a signal created on the cytoplasmic face of the spindle pole bodies (SPBs, functional equivalent of the ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-01-14 | PXD020369 | Pride
CDC5 is a conserved DNA-binding protein that is required for development and immunity. It promotes the accumulation of microRNAs (miRNAs) and endogenous small interfering RNAs (siRNAs), which repress gene expression. In this project, we aim to determine its global effect of on the accumulation of mi...
ORGANISM(S): Arabidopsis thaliana 
2018-03-01 | GSE104677 | GEO
Safeguarding Genome Integrity: Polo-like kinase Cdc5 and phosphatase Cdc14 Orchestrate Topoisomerase II-Mediated Catenane Resolution in Mitosis
Resolution of sister chromatid intertwine in mitosis is vital for safeguarding genome integrity. While cohesin, condensin, the polo-like kinase Cdc5, and the phosphatase Cdc14 have all been implicated in this process, the underlying molecular mechanisms remain elusive. Our study unveils a coordinati...
ORGANISM(S): Saccharomyces cerevisiae 
2025-12-18 | GSE294907 | GEO
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