Sort   by:  
 Page size 
UnknownInflammatory macrophages reprogram to immunosuppression by reducing mitochondrial translation.
Acute inflammation can either resolve through immunosuppression or persist, leading to chronic inflammation. These transitions are driven by distinct molecular and metabolic reprogramming of immune cells. The anti-diabetic drug Metformin inhibits acute and chronic inflammation through mechanisms sti...
S-EPMC10656499 | biostudies-literature
UnknownThe impact of MTHFR 677C → T risk knowledge on changes in folate intake: findings from the Food4Me study.

Background

It is hypothesised that individuals with knowledge of their genetic risk are more likely to make health-promoting dietary and lifestyle changes. The present study aims to test this hypothesis using data from the Food4Me study. This was a 6-month Internet-based randomised controlle...
S-EPMC5043523 | biostudies-literature
UnknownObjectively Measured Physical Activity in European Adults: Cross-Sectional Findings from the Food4Me Study.

Background

Comparisons of objectively measured physical activity (PA) between residents of European countries measured concurrently with the same protocol are lacking. We aimed to compare PA between the seven European countries involved in the Food4Me Study, using accelerometer data collecte...
S-EPMC4801355 | biostudies-literature
UnknownPrognostic value of patient-derived xenograft engraftment in pediatric sarcomas.
The goals of this work were to identify factors favoring patient-derived xenograft (PDX) engraftment and study the association between PDX engraftment and prognosis in pediatric patients with Ewing sarcoma, osteosarcoma, and rhabdomyosarcoma. We used immunodeficient mice to establish 30 subcutaneous...
S-EPMC8185364 | biostudies-literature
UnknownCharacteristics of European adults who dropped out from the Food4Me Internet-based personalised nutrition intervention.

Objective

To characterise participants who dropped out of the Food4Me Proof-of-Principle study.

Design

The Food4Me study was an Internet-based, 6-month, four-arm, randomised controlled trial. The control group received generalised dietary and lifestyle recommendations, whereas partici...
S-EPMC10261617 | biostudies-literature
UnknownClustering of adherence to personalised dietary recommendations and changes in healthy eating index within the Food4Me study.

Objective

To characterise clusters of individuals based on adherence to dietary recommendations and to determine whether changes in Healthy Eating Index (HEI) scores in response to a personalised nutrition (PN) intervention varied between clusters.

Design

Food4Me study participants we...
S-EPMC10270865 | biostudies-literature
UnknownEffects of a Web-Based Personalized Intervention on Physical Activity in European Adults: A Randomized Controlled Trial.

Background

The high prevalence of physical inactivity worldwide calls for innovative and more effective ways to promote physical activity (PA). There are limited objective data on the effectiveness of Web-based personalized feedback on increasing PA in adults.

Objective

It is hypothes...
S-EPMC4642412 | biostudies-literature
UnknownFTO genotype and weight loss: systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials.

Objective

 To assess the effect of the FTO genotype on weight loss after dietary, physical activity, or drug based interventions in randomised controlled trials.

Design

 Systematic review and random effects meta-analysis of individual participant data from randomised controlled trials...
S-EPMC6168036 | biostudies-literature
UnknownReproducibility of the Online Food4Me Food-Frequency Questionnaire for Estimating Dietary Intakes across Europe.

Background

Accurate dietary assessment is key to understanding nutrition-related outcomes and is essential for estimating dietary change in nutrition-based interventions.

Objective

The objective of this study was to assess the pan-European reproducibility of the Food4Me food-frequency...
S-EPMC6636390 | biostudies-literature
UnknownChanges in Physical Activity Following a Genetic-Based Internet-Delivered Personalized Intervention: Randomized Controlled Trial (Food4Me).

Background

There is evidence that physical activity (PA) can attenuate the influence of the fat mass- and obesity-associated (FTO) genotype on the risk to develop obesity. However, whether providing personalized information on FTO genotype leads to changes in PA is unknown.

Objective

...
S-EPMC4761101 | biostudies-literature
Sort   by:  
 Page size