Cell fate decision

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Department of Translational Medicine and Physiology, Washington State University, Spokane, WA, USA (1)
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Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, Shaanxi Province, China. (1)
Max-Planck-Institute for Biology of Ageing Department of Mitochondrial Proteostasis Joseph-Stelzmann-Str. 9b 50931 Cologne (1)
Professor Wellcome-Trust/ DBT India alliance fellow Head, Laboratory of Molecular Biology School of Biological Sciences Indian Association For The Cultivation Of Science (1)
Thomas Langer Max-Planck-Institute for Biology of Ageing Department of Mitochondrial Proteostasis Joseph-Stelzmann-Str. 9b 50931 Cologne (1)
University Regensburg,Department of Biochemistry, geneticsand Microbiology, Chair of Biochemistry I (1)
Zhejiang University (1)

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Kollarovic2016 - Cell fate decision at G1-S transition

Kollarovic2016 - Cell fate decision at G1-S transition This model is described in the article: To senesce or not to senesce: how primary human fibroblasts decide their cell fate after DNA damage. Kollarovic G, Studencka M, Ivanova L, Lauenstein C, Heinze K, Lapytsko A, Talem...

2024-09-02 | BIOMD0000000632 | BioModels

Hat2016 - Reponse of p53 System to irradiation in cell fate decision making

The p53 transcription factor is a regulator of key cellular processes including DNA repair, cell cycle arrest, and apoptosis. In this theoretical study, we investigate how the complex circuitry of the p53 network allows for stochastic yet unambiguous cell fate decision-making. The proposed Markov ch...

2024-09-02 | BIOMD0000000943 | BioModels

RNA-Seq profiling unveils a non-canonical Wnt signalling signature in pancreas versus liver fate decision

Understanding how distinct cell types arise from common multipotent progenitor cells is a major quest in stem cell biology. This knowledge will aid in the targeted differentiation and growth of stem cells, but also in the discovery of the basis of cellular plasticity and of how tissue programming ca...

ORGANISM(S): Mus musculus

2013-09-11 | E-GEOD-40823 | biostudies-arrayexpress

Stepwise cell fate decision pathways during osteoclastogenesis at single-cell resolution

PRJNA613258 | ENA

Arid3a modulates the first cell fate decision by direct regulation of both embryonic and extraembryonic gene expression (ChIP-Seq)

Arid3a, a transcription factor known for its requirement in B-lymphocyte development, has been recently identified as a member of ES cell pluripotency network. Arid3a is moderately expressed in ES cells, and its expression is gradually increased during differentiation. Since Arid3a shows the highest...

ORGANISM(S): Mus musculus

2014-10-16 | E-GEOD-56876 | biostudies-arrayexpress

Cell fate inclination within 2-cell and 4-cell mouse embryos revealed by single-cell RNA sequencing

It remains an open question when and how the first cell fate decision is made in mammals. Using deep single-cell RNA-seq of matched sister blastomeres, we report highly reproducible interblastomere differences among ten 2-cell and five 4-cell mouse embryos. Inter-blastomere gene expression differenc...

ORGANISM(S): Mus musculus

2014-07-29 | E-GEOD-57249 | biostudies-arrayexpress

Cell fate decision by a morphogen-transcription factor-chromatin modifier axis

PRJNA1015164 | ENA

Telomere Shortening Impairs PGC Fate Decision [RNA-seq]

PRJNA660794 | ENA

Telomere Shortening Impairs PGC Fate Decision [ATAC-seq]

PRJNA660789 | ENA

Cell competition regulates the fate decision of neural stem cells

PRJNA925106 | ENA