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Nutrient-deprived microalgae accumulate triacylglycerol (TAG) in lipid droplets. A Dual-specificity tyrosine phosphorylation-regulated kinase, TAG-accumulation-regulator-1 (TAR1) has been shown to be required for acetate-dependent TAG accumulation and degradation of chlorophyll and photosynthesis-re...
ORGANISM(S): Chlamydomonas 
MyD88-independent signal transduction associated with Toll-like receptors (TLRs) 3 and TLR4 is mediated through the adapter protein TRIF (TIR-domain-containing adapter-inducing interferon-beta). It has been proposed that TLR signalling is important for the transcription of crucial inflammasome compo...
ORGANISM(S): Mus musculus 
A label-free proteome analysis comparing changes in protein profiles of decidualized endometria and trophoblasts among women with different pregnancy outcomes, specifically a viable intrauterine pregnancy (IUP), ectopic pregnancy (EP), or early pregnancy loss (EPL), that identify potential biomarker...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-12-16 | MSV000088572 | MassIVE
TMT-based proteomic and phosphoproteomic analysis of mouse embryonic stem cells upon deletion of Ogt.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-11-16 | MSV000088393 | MassIVE
Nutrient-deprived microalgae accumulate triacylglycerol (TAG) in lipid droplets. A dual-specificity tyrosine phosphorylation-regulated kinase, TAG accumulation regulator 1 (TAR1) has been shown to be required for acetate-dependent TAG accumulation and the degradation of chlorophyll and photosynthesi...
ORGANISM(S): Cellular Organisms 
Exposure of eEC and eSF to SP in vitro increases expression of genes and secreted proteins associated with cellular migration, proliferation, viability and inhibition of cell death. This is a cross sectional study involving control samples versus treatment. SP (pooled from twenty donors) was first t...
ORGANISM(S): Homo sapiens 
This model explores the temporal dynamics of silver nanoparticles (AgNPs)-induced apoptosis using dynamic simulations in COPASI. It provides a time-resolved framework for understanding how cellular stress progresses to programmed cell death.
2025-09-08 | MODEL2412210001 | BioModels
The Oxidative Cost of Losing Low Temperature Viability Protein 1 [Ltv1]: Insights into Cellular Damage and Homeostasis
Histone deacetylases (HDACs) are critical in the control of gene expression and dysregulation of their activity has been implicated in a broad range of diseases including cancer, cardiovascular and neurological diseases. HDAC inhibitors (HDACi) employing different zinc chelating functionalities such...
ORGANISM(S): Homo sapiens 
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