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TranscriptomicsIdentification of genes expressed preferentially in the developing peripheral margin of the optic cup
Identification of genes expressed in a preferential manner in the developing ciliary body/iris will provide a starting point for future functional analyses. To identify candidate genes expressed in a variety of ocular tissues during development, we have profiled single cells from the developing eye...
ORGANISM(S): Mus musculus 
2009-05-01 | E-GEOD-15566 | biostudies-arrayexpress
TranscriptomicsGENE EXPRESSION CHANGES WITHIN MM-CM-^\LLER GLIAL CELLS DURING RETINITIS PIGMENTOSA
Retinitis Pigmentosa (RP) is a progressive retinal degeneration in which the retina loses nearly all of its photoreceptor cells and undergoes major structural changes. Little is known regarding the role the resident glia, the MM-CM-
ORGANISM(S): Mus musculus 
2014-10-31 | E-GEOD-35386 | biostudies-arrayexpress
TranscriptomicsDevelopment and Diversification of Retinal Amacrine Interneurons at Single Cell Resolution
The vertebrate retina uses diverse neuronal cell types arrayed into complex neural circuits to extract, process and relay information from the visual scene to the higher order processing centers of the brain. Amacrine cells, a diverse class of inhibitory interneurons, are thought to mediate the maj...
ORGANISM(S): Mus musculus 
2009-05-31 | E-GEOD-12601 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse single retinal cells reveals individual retinal progenitor cells display extensive heterogeneity of gene expression
The development of complex tissues requires that mitotic progenitor cells integrate information from the environment. The highly varied outcomes of such integration processes undoubtedly depend at least in part upon variations among the gene expression programs of individual progenitor cells. To dat...
ORGANISM(S): Mus musculus 
2008-06-17 | E-GEOD-9811 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse developing retinal ganglion and amacrine cells reveals molecular heterogeneity of
During development of the central nervous system (CNS), cycling uncommitted progenitor cells give rise to a variety of distinct neuronal and glial cell types. As these different cell types are born, they progress from newly specified cells to fully differentiated neurons and glia. In order to defi...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9812 | biostudies-arrayexpress
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