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ProteomicsAcute lymphoblastic leukemia in children produces endogenous T-cells targeting tumor associated antigens and neoantigens in peripheral blood
In this study we investigated the presence of endogenous T-cells recognizing private tumor-associated antigens and predicted neoantigens. To this end, HLA-I and HLA-II restricted tumor associated antigens (TAAs) and neoantigens were respectively identified and predicted. Of interest, circulating T-c...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD061914 | Pride
Human Pediatric leukemia Mass spectrometry Antigen discovery 
TranscriptomicsmicroRNA profiling of ovary cell tumors and HOSE cells
In order to determine the difference at the microRNA level of different ovarian tumor histotypes, we have performed a whole miRNA screening on 183 patients of grade 1 ovarian cancer. Additionally, we compared the miRNA profile of tumors with standard ovarian epithelial cells (HOSE).
ORGANISM(S): Homo sapiens 
2013-06-17 | E-MTAB-1067 | biostudies-arrayexpress
TranscriptomicsmiR-155 KO in human dendritic cells
In response to inflammatory stimulation, dendritic cells (DCs) have a remarkable pattern of differentiation (maturation) that exhibits specific mechanisms to control immunity. Here, we show that in response to Lipopolysaccharides (LPS), several microRNAs (miRNAs) are regulated in human monocyte-deri...
ORGANISM(S): Homo sapiens 
2009-03-04 | E-GEOD-13296 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profiling of human monocyte-derived dendritic cells (moDCs) during maturation
miRNA expression profiling of human monocyte-derived dendritic cells (moDCs) during maturation. Immature, 4h and 16h LPS-activated moDCs were used. In this study were analysed 2 biological samples of RNA extracted from 4h-post LPS stimulation moDCs and 2 bfrom 16h-post LPS stimulation. The RNA ...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-13369 | biostudies-arrayexpress
UnknownCD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response.
Not available
S-EPMC5474321 | biostudies-literature
ProteomicsEffect of TOPBEffect of TOPBP1 on BLM phosphosites
Identification of BLM phosphosites. The experiment is composed by 2 parts: i) identification of BLM phosphosites with DDA method ii) quantification of phosphosites with a targeted method.
ORGANISM(S): Homo sapiens (Human) 
2021-11-25 | PXD026460 | Pride
Phosphosites 
Unknown<i>In silico</i> characterization of the interaction of AKR1B1 with the deacetylase activation domain (DAD).
Not available
S-EPMC12040874 | biostudies-literature
UnknownThe chaperone activity of 4PBA ameliorates the skeletal phenotype of Chihuahua, a zebrafish model for dominant osteogenesis imperfecta.
Not available
S-EPMC5886106 | biostudies-literature
UnknownCharacterization and diagnostic application of genomic NPM-ALK fusion sequences in anaplastic large-cell lymphoma.
Not available
S-EPMC5995187 | biostudies-literature
Unknown5' Region Large Genomic Rearrangements in the BRCA1 Gene in French Families: Identification of a Tandem Triplication and Nine Distinct Deletions with Five Recurrent Breakpoints.
Not available
S-EPMC8268747 | biostudies-literature
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