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TranscriptomicsPancreatic gene expression associated with cerulein induced chronic pancreatitis in mice
A frequently used experimental model of chronic pancreatitis (PC) recapitulating human disease is repeated injection of cerulein to mice. We found that two common substrains of C57BL/6 , C56BL/6J (Jackson) and C57BL/6NHsd (Harlan), exhibit different degree of CP with C57BL/6J beeing more susceptible...
ORGANISM(S): Mus musculus 
2012-10-10 | E-GEOD-41418 | biostudies-arrayexpress
GenomicsExpression Data from Cerulein Treated Pancreas
Expression Data from Cerulein Treated Pancreas
PRJNA499083 | ENA
TranscriptomicsExpression Data from Cerulein Treated Pancreas
IFRD1 is required for reserve stem cell proliferation in multiple tissues. Repeated cerulein treatment causes damage and induces proliferation in otherwise terminally differentiated pancreatic acinar cells. We used microarrays to detail gene expression changes in IFRD1 null mice treated with cerulei...
ORGANISM(S): Mus musculus 
2020-06-01 | GSE121925 | GEO
TranscriptomicsRNA-sequencing of isolated pancreatic acinar cells from RalGAPβ knockout mice against control mice treated with cerulein
Pancreatic RalGAPβ deficiency induces inflammation and neoplasia. RNA sequencing of isolated acinar cells of cerulein treated mice was performed 24 hours after treatment to identify underlying processes in defective acinar regeneration.
ORGANISM(S): Mus musculus 
2025-06-03 | E-MTAB-15030 | biostudies-arrayexpress
GenomicsScreening regulated pathway and genes expression in polyI:C treated cerulein-induced AP mice models
Screening regulated pathway and genes expression in polyI:C treated cerulein-induced AP mice models
PRJNA490448 | ENA
TranscriptomicsScreening regulated pathway and genes expression in polyI:C treated cerulein-induced AP mice models
Pancreas tissue derived from mice with intraperitoneal injection of saline, cerulein or polyI:C plus cerulein, total RNA was extracted and deep sequenced to compare the gene expression profiles among control, acute pancreatitis and intervention of polyI:C on acute pancreatitis.
ORGANISM(S): Mus musculus 
2019-05-15 | GSE119844 | GEO
TranscriptomicsPancreatic gene expression associated with cerulein induced chronic pancreatitis in mice
A frequently used experimental model of chronic pancreatitis (PC) recapitulating human disease is repeated injection of cerulein to mice. We found that two common substrains of C57BL/6 , C56BL/6J (Jackson) and C57BL/6NHsd (Harlan), exhibit different degree of CP with C57BL/6J beeing more susceptible...
ORGANISM(S): Mus musculus 
2012-10-10 | GSE41418 | GEO
ProteomicsTemporal Proteomic and Lipidomic Profiles of Cerulein-Induced Acute Pancreatitis Reveals Novel Insights for Metabolic Alterations in the Disease Pathogenesis
The pathophysiological mechanisms of acute pancreatitis (AP) are complex and have remained a mystery to date, but metabolism is gradually recognized as an important driver of AP onset and development. We used a cerulein-induced AP mouse model to conduct LC-MS/MS based time-course proteomics and lipi...
ORGANISM(S): Mus Musculus 
2022-12-06 | PXD038567 |
GenomicsRNA-sequencing of isolated pancreatic acinar cells from RalGAPβ knockout mice against control mice treated with cerulein
RNA-sequencing of isolated pancreatic acinar cells from RalGAPβ knockout mice against control mice treated with cerulein
PRJEB88557 | ENA
GenomicsCerulein induced acute pancreatitis in C57Bl/6J
Cerulein induced acute pancreatitis in C57Bl/6J
PRJNA430220 | ENA
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