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GenomicsPiscirickettsia salmonis CGA/3731
Piscirickettsia salmonis CGA/3731 Genome sequencing
PRJNA232514 | ENA
ProteomicsChlorogenic acid mitigates calcium oxalate monohydrate crystal-induced epithelial-to-mesenchymal transition in renal epithelial cells via suppression of HSP60 expression and p38 signaling
Background: Epithelial-to-mesenchymal transition (EMT) is a prominent process involved in kidney fibrosis. Calcium oxalate monohydrate (COM), a crystalline composition predominantly found in renal stones, is one of the known stimuli that can trigger the EMT process. Chlorogenic acid (CGA), a phenoli...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2026-09-14 | PXD076150 | Pride
Cellular proteome  cga  emt  hsp60  kidney fibrosis  proteomics 
GenomicsRNA Sequencing Facilitates Quantitative Analysis of shL3MBTL2 ,CGA-OE and corresponding control Transcriptomes
RNA Sequencing Facilitates Quantitative Analysis of shL3MBTL2 ,CGA-OE and corresponding control Transcriptomes
PRJNA766629 | ENA
GenomicsChromogranin A (CgA) Deficiency Attenuates Tauopathy by Altering Epinephrine–Alpha-Adrenergic Receptor Signaling
Chromogranin A (CgA) Deficiency Attenuates Tauopathy by Altering Epinephrine–Alpha-Adrenergic Receptor Signaling
PRJNA1146456 | ENA
GenomicsRNA Sequencing Analysis between Control and CGA knockdown Multi-drug resistant Cells
RNA Sequencing Analysis between Control and CGA knockdown Multi-drug resistant Cells
PRJNA797436 | ENA
TranscriptomicsChromogranin A (CgA) Deficiency Attenuates Tauopathy by Altering Epinephrine–Alpha-Adrenergic Receptor Signaling
Our previous studies have indicated that insulin resistance, hyperglycemia, and hypertension in aged wild-type (WT) mice can be reversed in mice lacking chromogranin-A (CgA-KO mice). These health conditions are associated with a higher risk of Alzheimer’s disease (AD). CgA, a neuroendocrine secretor...
ORGANISM(S): Mus musculus 
2025-04-07 | GSE274459 | GEO
TranscriptomicsRNA Sequencing Facilitates Quantitative Analysis of shL3MBTL2 ,CGA-OE and corresponding control Transcriptomes
L3MBTL2 is a crucial component of ncPRC1.6 and has been implicated in transcriptional repression and chromatin compaction. However, the repression mechanism of L3MBTL2 and its biological functions are largely undefined. CGA encodes the alpha subunit of glycoprotein hormones, however, we showed that ...
ORGANISM(S): Homo sapiens 
2022-01-01 | GSE184834 | GEO
ProteomicsLactylation of NAT10 promotes N4‐acetylcytidine modification on tRNASer-CGA-1-1 to boost oncogenic DNA virus KSHV reactivation
N4-acetylcytidine (ac4C), a conserved but recently rediscovered RNA modification on tRNAs, rRNAs and mRNAs, is catalyzed by N-acetyltransferase 10 (NAT10). Lysine acylation is a ubiquitous protein modification that controls protein functions. Our latest study demonstrates a NAT10-dependent ac4C modi...
ORGANISM(S): Homo Sapiens 
2024-04-26 | PXD049447 |
ClinicalEffect of CGA for Frail Elderly Patients Operated for Colorectal Cancer - The CRC Frailty-study
This multicentre randomized controlled trial aims to investigate whether an individualized comprehensive geriatric assessment (CGA) and care will improve postoperative results in frail elderly patients undergoing surgery for colorectal cancer. The study will take place in departments applying the ER...
2336924 | ecrin-mdr-crc
TranscriptomicsRNA Sequencing Analysis between Control and CGA knockdown Multi-drug resistant Cells
The aim of this study is to compare the CGA Knockdown multi-drug resistant (MDR) cells (SGC7901/ADR and SGC7901/VCR) to the control cells. The total RNA of the indicated cells were extracted using Qiagen RNA Extraction Kit and RNA sequencing was performed. Significant differences in genes and signal...
ORGANISM(S): Homo sapiens 
2022-03-30 | GSE193739 | GEO
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