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TranscriptomicsValidation of a subset of copy number variants from GSE24424 by aCGH
This dataset was used to validate CNV predictions from GSE24424. We designed a custom CGH array to interrogate a total of 4,420 individual CNVs and their flanks predicted in 17 individuals. On the basis of a test that compares signals of probes located within to those mapping outside of CNVs (two-ta...
ORGANISM(S): Mus musculus 
2010-12-31 | E-GEOD-24640 | biostudies-arrayexpress
TranscriptomicsCopy number variation in inbred and wild mice
Copy number variants were determined in 3-5 males from 13 inbred laboratory mouse strains and 21 Mus musculus individuals caught in various geographic locations, using Nimblegen 385k arrays. CopyMap was used to predict CNVs. 3-5 males from 13 inbred strains and 21 Mus musculus caught in various geog...
ORGANISM(S): Mus spretus 
2010-12-31 | E-GEOD-24424 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of mouse tissues from different mouse strains to investigate the effects of copy number variation on gene expression
Copy number variation (CNV) of DNA segments has recently been identified as a major source of genetic diversity, but a more comprehensive understanding of the extent and phenotypic effect of this type of variation is only beginning to emerge. In this study we generated genome-wide expression data fr...
ORGANISM(S): Mus musculus 
2009-02-28 | E-GEOD-10744 | biostudies-arrayexpress
TranscriptomicsThe influence of segmental copy number variation on tissue transcriptomes through development
A preliminary understanding of the phenotypic effect of copy number variation (CNV) of DNA segments is emerging. These rearrangements were demonstrated to influence, in a somewhat dose-dependent manner, the expression of genes mapping within. They were shown to also affect the expression of genes lo...
ORGANISM(S): Mus musculus 
2010-11-17 | E-GEOD-16675 | biostudies-arrayexpress
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