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TranscriptomicsTranscription profiling of human colon biopsies obtained from patients with ulcerative colitis, Chrohn's disease vs. normal to identify pathogenic processes underlying these disease subtypes
Ulcerative colitis (UC) and Crohn’s disease (CD) are inflammatory bowel diseases (IBD) with variable, overlapping clinical features and complex pathophysiologies. To identify pathogenic processes underlying these disease subtypes, using single endoscopic pinch biopsies to estabolish 36 expression pr...
ORGANISM(S): Homo sapiens 
2007-11-02 | E-GEOD-6731 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse primary cultures from mouse cornea vs those of the adult and 10-day postnatal mouse cornea to elucidate biological processes underlying the keratocyte, fibroblast, and myofibroblast phenotypes of corneal stromal cells
To elucidate biological processes underlying the keratocyte, fibroblast, and myofibroblast phenotypes of corneal stromal cells, the gene expression patterns of these primary cultures from mouse cornea were compared with those of the adult and 10-day postnatal mouse cornea.
ORGANISM(S): Mus musculus 
2007-10-31 | E-GEOD-1867 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse developing and adult cornea compared to the lens and tendon
The cornea continues to mature after birth to develop a fully functional, refractive and protective barrier tissue. Here we investigated the complex biological events underlying this process by profiling global genome-wide gene expression patterns of the immature postnatal day 10 and seven week-old ...
ORGANISM(S): Mus musculus 
2008-10-21 | E-GEOD-11900 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human sigmoid colon biopsies from healthy and patients with ulcerative colitis
Gene expression profiles were performed to compare the difference in sigmoid colon biopsies between from healthy control and patients with ulcerative colitis. Experiment Overall Design: Total RNA was isolated sigmoid biopdy from 5 healthy and 6 UC patients. Pooled 5 ug total RNA equally for each gr...
ORGANISM(S): Homo sapiens 
2009-03-07 | E-GEOD-10791 | biostudies-arrayexpress
ProteomicsA proteomic map of the human aqueous humor
The aqueous humor is a colourless, transparent fluid that fills the anterior chamber of the eye. It has an important role to play in maintaining the intraocular pressure of the eye and providing nourishment to avascular structures such as the lens and cornea. It is also essential for providing a cle...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-29 | MSV000081764 | MassIVE
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