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TranscriptomicsmicroRNAs in C. elegans, P. pacificus, and S. ratti: Conserved miRNAs are candidate post-transcriptional regulators of developmental arrest in free-living and parasitic nematodes
Animal development is complex yet surprisingly robust. Animals may develop alternative phenotypes conditional on environmental changes. Under unfavorable conditions C. elegans larvae enter the dauer stage, a developmentally arrested, long-lived, and stress-resistant state. Dauer larvae of free-livin...
ORGANISM(S): Pristionchus pacificus 
2013-07-04 | E-GEOD-41402 | biostudies-arrayexpress
Proteomics2020_Human BAK125 kit _Room Temperature
We assessed the impact of leaving a lyophilized mixture consisting of 125 peptides at room temperature for up to 20 days, and we assessed the effect on the quantitative performance of multiple reaction monitoring-MS (MRM-MS) assays. The findings suggest that there are no significant differences in t...
ORGANISM(S): Homo Sapiens 
2022-09-05 | PXD028179 | panorama
TranscriptomicsRNA-seq of Chlamydomonas reinhardtii exposed to inorganic or methylmercury
This study aims at investigating the link between internalized inorganic or methyl Hg and the global expression of genes, obtained by high-throughput sequencing (RNA-Seq), in the microalga Chlamydomonas reinhardtii. Algal cells were exposed two hours in a simplified artificial medium spiked with ser...
ORGANISM(S): Chlamydomonas reinhardtii 
2017-06-27 | E-GEOD-65109 | biostudies-arrayexpress
TranscriptomicsRNA Affinity Purification followed by sequencing (RAP-seq) allows identification of transcriptome-wide RBP binding sites using recombinant RBPs and purified total cellular RNA
RAPseq is a new in vitro method used to study RNA-protein interactions at scale. In RAPseq, a recombinant RBP is produced as fusion with a HaloTag which is used to recover and purify the RBP of interest. The RBP-Halo fusion is then incubated with fragmented native total RNA that retains endogenous s...
ORGANISM(S): Homo sapiens 
2023-12-29 | E-MTAB-10834 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of C3H/HeJ and JF1/Msf strain mice to identify genetic risk factors for asthma and COPD
Comparison of lung function in C3H/HeJ and JF1/Msf strain mice to identify genetic risk factors for asthma and COPD.
ORGANISM(S): Mus musculus 
2007-03-08 | E-MEXP-855 | biostudies-arrayexpress
TranscriptomicsIntegrative phenotypic and transcriptomic validation of an alveolar-like macrophage model reveals early host–pathogen dynamics during Aspergillus fumigatus infection
The saprophytic mold Aspergillus fumigatus produces small (2-3 µm) airborne spores (conidia) that can reach the lung alveoli upon inhalation. There, they encounter the surfactant-rich environment of the alveolar epithelium and initiate swelling and germination. Primary alveolar macrophages are essen...
ORGANISM(S): Homo sapiens 
2026-10-02 | E-MTAB-17130 | biostudies-arrayexpress
no omics definedHodgkin_IV-IIIB_Ben-Dov_CRG
Hodgkin lymphoma derived cell lines (from the Deutsche Sammlung von Mikroorganismen und Zellkulturen) were cultured in RPMI 1640 medium supplemented with

20% (HDML-2) or 10% (HD-MY-Z) heat inactivated fetal calf serum. Cytoplasmic RNA was extracted according to "Cytoplasmic_RNA_CRG" protocol...
ORGANISM(S): Homo sapiens 
2010-12-31 | E-MEXP-2959 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of breast tissue from chickens with low and high body weights
A study of a marked QTL affecting body weight segregating in an inter-cross of a broiler and layer chickens. QTL genotypes were inferred on flanking markers and RNA from breast tissue of birds with alternative QTL genotypes was hybridized onto microarrays
ORGANISM(S): Gallus gallus 
2010-07-20 | E-TABM-475 | biostudies-arrayexpress
GenomicsDNA hypomethylation bypasses the interploidy hybridization barrier in Arabidopsis
Plants of different ploidy levels are separated by a strong postzygotic hybridization barrier that is established in the endosperm. Deregulated parent-of-origin specific genes are causal for the response to interploidy hybridizations, revealing an epigenetic basis of this phenomenon. In this study w...
ORGANISM(S): Arabidopsis thaliana 
2014-09-22 | E-GEOD-53642 | biostudies-arrayexpress
TranscriptomicsMetabolic and transcriptional activities of Staphylococcus aureus challenged with high-doses of daptomycin
Treatment of stationary growth phase Staphylococcus aureus SA113 with 100-fold of the MIC of the lipopeptide antibiotic daptomycin leaves alive a small fraction of drug tolerant albeit genetically susceptible bacteria. This study shows that cells of this subpopulation exhibit active metabolism even ...
ORGANISM(S): Staphylococcus aureus 
2014-06-06 | E-GEOD-57908 | biostudies-arrayexpress
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