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TranscriptomicsEvolutionary divergence in the fungal response to fluconazole revealed by soft clustering (S. cerevisiae, C. glabrata, K. lactis)
Fungal infections are an emerging health risk, especially those involving yeast that are resistant to antifungal agents. To understand the range of mechanisms by which yeasts can respond to anti-fungals, we compared gene expression patterns across three evolutionarily distant species - Saccharomyces...
ORGANISM(S): Candida glabrata 
2010-07-08 | E-GEOD-15710 | biostudies-arrayexpress
TranscriptomicsCoeevolution of a transcriptional network by compensatory trans and cis mutations
Transcriptional networks have been shown to evolve very rapidly, prompting questions as to how such changes arise and are tolerated. Recent comparisons of transcriptional networks across species have implicated variations in the cis-acting DNA sequences near genes as the main cause of divergence. Wh...
ORGANISM(S): Candida glabrata 
2010-09-17 | E-GEOD-15818 | biostudies-arrayexpress
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