Chandler Dave D

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Gene Expression Signature in Adipose Tissue of Acromegaly Patients

OBJECTIVE: Acromegaly is a rare endocrine disorder with excess growth hormone (GH) production. This disorder has important metabolic effects in insulin resistance and lipolysis. The objective of this study was to explore transcriptional changes induced by GH in adipose tissue. METHODS: The patients ...

ORGANISM(S): Homo sapiens

2015-05-01 | E-GEOD-57803 | biostudies-arrayexpress

The Cushing's disease adipose gene expression profile reveals effects of long term glucocorticoids on adipose tissue lipid, protein and glucose metabolism

Glucocorticoids have major effects on adipose tissue metabolism. To study tissue mRNA expression changes induced by chronic elevated endogenous glucocorticoids, we performed RNA sequencing on subcutaneous adipose tissue from patients with Cushing’s disease (n=5) compared to patients with non-functio...

ORGANISM(S): Homo sapiens

2015-08-01 | E-GEOD-66446 | biostudies-arrayexpress

Current use of drains and management of seroma following mastectomy and axillary surgery: results of a United Kingdom national practice survey.

Not available

S-EPMC10787912 | biostudies-literature

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.

Not available

S-EPMC8830904 | biostudies-literature

Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.

Not available

S-EPMC10957483 | biostudies-literature

Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial.