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TranscriptomicsGene expression in primary human B cells sorted according to IL-10 secretion or not after 2 days of activation.
To determine characterize human B cells that express IL-10 on a molecular level, we compared the global gene expression of primary CD19pos B cells secreting IL-10 or not, upon activation with anti-CD40, IL-4 and CpG for 2 days. Human B cells from healthy donors were sorted according to CD19 expressi...
ORGANISM(S): Homo sapiens 
2014-03-24 | E-GEOD-49853 | biostudies-arrayexpress
ProteomicsNano LC-MS/MS DDA mass spectrometry profiling of I-Ab MHCII immunopeptidome eluted from B6 mice on normal and high fructose/high fat (HFHF) diet
In Dendritic cells (DC), the MHC II eluted immunopeptidome reflects the antigenic composition of the microenvironment. Proteins are transported and processed into peptides in endosomal MHC II compartments through autophagy or phagocytosis; extracellular peptides can also directly bind MHC II protein...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-22 | PXD026068 | Pride
Mouse i-ab immunopeptidome  dda nanolc-ms/ms  orbitrap fusion tribrid mass spectrometer 
UnknownInstability of toxin A subunit of AB(5) toxins in the bacterial periplasm caused by deficiency of their cognate B subunits.
Not available
S-EPMC5007120 | biostudies-literature
TranscriptomicsAB family 1
Array comparative genomic hybridization was used to identify genomic differences between male and female zebrafish. No universal sex-linked CNVR was identified. AB strain of zebrafish were used.The family consist of the parents and 2 male and female offspring each (total 6 samples). Dad's gDNA was u...
ORGANISM(S): Danio rerio 
2012-04-16 | E-GEOD-34334 | biostudies-arrayexpress
TranscriptomicsAB family 2
Array comparative genomic hybridization was used to identify genomic differences between male and female zebrafish. No universal sex-linked CNVR was identified. AB strain of zebrafish were used.The family consist of the parents and 2 male and female offspring each (total 6 samples). Dad's gDNA was u...
ORGANISM(S): Danio rerio 
2012-04-16 | E-GEOD-34335 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP6.0 array data for different clinical outcomes of HBV infection
Chronic hepatitis B virus (HBV) infection is a serious global public health problem. To identify susceptibility loci for disease progression of HBV infection, we performed this genome-wide association study using DNA pools of case and control constructed by progressed HBV carriers (acute liver failu...
ORGANISM(S): Homo sapiens 
2013-12-10 | E-GEOD-26034 | biostudies-arrayexpress
MetabolomicsChromosome‐level genome of Camellia lanceoleosa provides a valuable resource for understanding genome evolution and self‐incompatibility

The section Oleifera (Theaceae) has attracted attention for the high levels of unsaturated fatty acids found in its seeds. Here, we report the chromosome-scale genome of the sect. Oleifera using diploid wild Camellia lanceoleosa with a final size of 3.00 Gb and an N50 s...

2022-07-14 | MTBLS3769 | MetaboLights
ProteomicsB-Cell-based Therapy Controls Glioblastoma Growth by Producing Antibodies that Inhibit Tumor Invasion and Migration
Glioblastoma multiforme (GBM) is a highly aggressive and malignant brain tumor with limited therapeutic options and poor prognosis. Despite current treatments, the invasive nature of GBM often leads to recurrence. A promising alternative strategy is to harness the immune system's potential against t...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2024-09-10 | PXD046712 | Pride
Glioblastoma multiforme (gbm)  b-cell-based vaccine (bvax)  tumor-reactive antibodies  immunoproteomics 
MetabolomicsFlavonoid Biosynthesis Is Likely More Susceptible to Elevation and Tree Age Than Other Branch Pathways Involved in Phenylpropanoid Biosynthesis in Ginkgo Leaves
Ginkgo leaves are always resources for flavonoids pharmaceutical industry. However, the effect of the elevation and tree age changes on flavonoid biosynthesis have not been detailly explored in Ginkgo leaves. In addition, whether these environmental pressures have similar effects on the biosynthesis...
2020-12-14 | MTBLS962 | MetaboLights
MetabolomicsMultiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers

BACKGROUND: Clonorchiasis, an infectious disease caused by the liver fluke Clonorchis sinensis, may lead to the development of liver and gallbladder diseases, and even cholangiocarcinoma (CCA). However, the pathogenesis, host-pathogen interaction, and diagnostic markers ...

2022-06-24 | MTBLS3306 | MetaboLights
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