Bile salt hydrolase is a cysteine hydrolase that catalyzes the deconjugation of amino acids from bile acid amidates. The catalytic residue, cysteine 2, must be in a thiolate form for hydrolysis to occur. Using a chemical probe, CA-Dim (file name suffix 'D'), we identified cysteine 2 reversibly forms...
ORGANISM(S): Mus musculus (Mouse)