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TranscriptomicsIntraspecific variation in the Populus balsamifera drought transcriptome
Drought is a major limitation to the growth and productivity of trees in the ecologically and economically important genus Populus. The ability of Populus trees to contend with drought is a function of the responsiveness of their genome to this environmental insult, involving reconfiguration of the ...
ORGANISM(S): Populus balsamifera 
2010-12-31 | E-GEOD-21171 | biostudies-arrayexpress
TranscriptomicsDistinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_Stability]
TDP-43, FUS, and TAF15 are implicated in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. We integrate CLIP-seq and RNA Bind-N-Seq technologies to discover that TAF15 binds to ~4,900 RNAs enriched for GGUA motifs. In the mouse brain, TAF15 and FUS, but not TDP-43, exhibit strikingly ...
ORGANISM(S): Homo sapiens 
2016-07-05 | E-GEOD-77704 | biostudies-arrayexpress
TranscriptomicsDistinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_human]
TDP-43, FUS, and TAF15 are implicated in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. We integrate CLIP-seq and RNA Bind-N-Seq technologies to discover that TAF15 binds to ~4,900 RNAs enriched for GGUA motifs. In the mouse brain, TAF15 and FUS, but not TDP-43, exhibit strikingly ...
ORGANISM(S): Homo sapiens 
2016-07-05 | E-GEOD-77702 | biostudies-arrayexpress
TranscriptomicsClone History Shapes Populus Drought Responses
Just as animal monozygotic twins can experience different environmental conditions by being reared apart, individual genetically-identical trees of the genus Populus can also be exposed to contrasting environmental conditions by being grown in different locations. As such, clonally-propagated Popul...
ORGANISM(S): Populus hybrid sp. 'Walker' 
2011-05-01 | E-GEOD-27693 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of Kidney Glomeruli from Type 2 diabetic (db/db) and non-diabetic mice
We investigated the gene expression profiles of RNA isolated from kidney glomeruli from aged, 25 week old type-2 diabetic (db/db) and non-diabetic mice. In order to investigate the consequences of hyperglycemia on the pathogenesis and progression of diabetic nephropathy Kidney glomeruli from 3 diabe...
ORGANISM(S): Mus musculus 
2016-10-24 | E-GEOD-77717 | biostudies-arrayexpress
MetabolomicsMetabolome patterns identify active dechlorination in bioaugmentation consortium SDC-9

Ultra-high performance liquid chromatography-high resolution mass spectrometry (UPHLC-HRMS) is used to discover and monitor single or sets of biomarkers informing about metabolic processes of interest. The technique can detect thousands of molecules (i.e., metabolites) in a single instrument run ...

2022-09-16 | MTBLS5219 | MetaboLights
TranscriptomicsDistinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_mouse]
TDP-43, FUS, and TAF15 are implicated in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. We integrate CLIP-seq and RNA Bind-N-Seq technologies to discover that TAF15 binds to ~4,900 RNAs enriched for GGUA motifs. In the mouse brain, TAF15 and FUS, but not TDP-43, exhibit strikingly ...
ORGANISM(S): Mus musculus 
2016-07-05 | E-GEOD-77703 | biostudies-arrayexpress
TranscriptomicsTranscript profiling of UBIproPtMYB14 and CADproPtMYB14 in transgenic White spruce plantlets
Transcription factors play a fundamental role in plants by orchestrating temporal and spatial gene expression in response to environmental stimuli. Several R2R3-MYB genes of the Arabidopsis subgroup 4 (Sg4) share a C-terminal EAR motif signature recently linked to stress response in angiosperm plant...
ORGANISM(S): Picea glauca 
2012-03-01 | E-MEXP-3575 | biostudies-arrayexpress
TranscriptomicsDistinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [array]
TDP-43, FUS, and TAF15 are implicated in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. We integrate CLIP-seq and RNA Bind-N-Seq technologies to discover that TAF15 binds to ~4,900 RNAs enriched for GGUA motifs. In the mouse brain, TAF15 and FUS, but not TDP-43, exhibit strikingly ...
ORGANISM(S): Mus musculus 
2016-07-05 | E-GEOD-77699 | biostudies-arrayexpress
UnknownPostvaccination Immunogenicity Among Pediatric Solid Organ Transplant Recipients.
Not available
S-EPMC11851299 | biostudies-literature
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