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ProteomicsGlobal Analysis of Protein Folding Thermodynamics for Disease State Characterization, MCF7 vs MDAMB231
Protein biomarkers can be used to characterize and diagnose disease states such as cancer. They can also serve as therapeutic targets. Current methods for protein biomarker discovery, which generally rely on the large-scale analysis of gene and/or protein expression levels, fail to detect protein b...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080761 | MassIVE
ProteomicsGlobal Analysis of Protein Folding Thermodynamics for Disease State Characterization, MCF7 vs MCF10A
Protein biomarkers can be used to characterize and diagnose disease states such as cancer. They can also serve as therapeutic targets. Current methods for protein biomarker discovery, which generally rely on the large-scale analysis of gene and/or protein expression levels, fail to detect protein b...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080760 | MassIVE
ModelsProctor2011_ProteinHomeostasis_NormalCondition
This model is from the article: Modelling the Role of the Hsp70/Hsp90 System in the Maintenance of Protein Homeostasis Proctor CJ, Lorimer IAJ PLoS ONE2011; 6(7): e22038. doi:10.1371/journal.pone.0022038, Abstract: Neurodegeneration is a...
2024-09-02 | BIOMD0000000344 | BioModels
UnknownVisualizing the chaperone-mediated folding trajectory of the G protein β5 β-propeller.
Not available
S-EPMC10841713 | biostudies-literature
UnknownVisualizing the chaperone-mediated folding trajectory of the G protein β5 β-propeller.
Not available
S-EPMC10187262 | biostudies-literature
UnknownmRNA Engineering for the Efficient Chaperone-Mediated Co-Translational Folding of Recombinant Proteins in Escherichia coli.
Not available
S-EPMC6651523 | biostudies-literature
UnknownChemical Synthesis and Chaperone Peptide Mediated Folding of Human Nerve Growth Factor by Expressed KAHA Ligation.
Not available
S-EPMC12395302 | biostudies-literature
TranscriptomicsGenome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo
We present an approach for globally monitoring RNA structure in native conditions in vivo with single nucleotide precision. This method is based on in vivo modification with dimethyl sulfate (DMS), which reacts with unpaired adenine and cytosine residues9, followed by deep sequencing to monitor modi...
ORGANISM(S): Homo sapiens 
2013-12-15 | E-GEOD-45803 | biostudies-arrayexpress
UnknownBuilt-in RNA-mediated chaperone (chaperna) for antigen folding tailored to immunized hosts.
Not available
S-EPMC7262357 | biostudies-literature
TranscriptomicsTranslational profiling in the unfolded protein response
The unfolded protein response (UPR) couples cellular translation rates and gene expression to the protein folding status of the endoplasmic reticulum (ER). Upon activation, the UPR machinery elicits a general suppression of protein synthesis and activation of stress gene expression, which act coordi...
ORGANISM(S): Mus musculus 
2014-08-28 | E-GEOD-53743 | biostudies-arrayexpress
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