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TranscriptomicsAn integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer: gene expression
10 Breast cancer cell lines profiled on the Affymetrix U133 Plus 2.0 platform used in conjunction with matched DNA copy number and DNA methylation data for integrative analysis. In total, 10 samples were used. The MCF10A profile used as normal was obtained from GSM254525 and the remaining 2 cell lin...
ORGANISM(S): Homo sapiens 
2010-11-05 | E-GEOD-17768 | biostudies-arrayexpress
TranscriptomicsAn integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer: DNA methylation
Methylation profiles of a panel of breast cancer lines that were included in the integrative analysis of DNA copy number, allelic status, DNA methylation and gene expression. Methylation profiles of 9 breast cancer cell lines and one normal line were generated. Genes were determined to be hyper a...
ORGANISM(S): Homo sapiens 
2010-11-05 | E-GEOD-17769 | biostudies-arrayexpress
TranscriptomicsEffect of active smoking on bronchial epithelial transcriptome (24 SAGE libraries)
24 SAGE libraries comprising of 8 current smokers, 12 former smokers and 4 never smokers. Keywords: SAGE, gene expression, current, former, never, smokers Raw tag counts for each tag in each library are provided
ORGANISM(S): Homo sapiens 
2007-08-07 | E-GEOD-5473 | biostudies-arrayexpress
TranscriptomicsExpression profiling of normal lung parenchyma
2 normal lung parenchyma SAGE libraries, generated from 2 pools of 4 individuals each Discussed in the study: IDENTIFICATION OF NOVEL LUNG GENES IN BRONCHIAL EPITHELIUM BY SERIAL ANALYSIS OF GENE EXPRESSION Kim M. Lonergan1, Raj Chari1, Ronald J. deLeeuw1, Ashleen Shadeo1, Bryan Chi1, Ming-Sound T...
ORGANISM(S): Homo sapiens 
2006-11-20 | E-GEOD-3708 | biostudies-arrayexpress
TranscriptomicsDNA copy number and gene expression profiles of resected non-small cell lung cancer tumors
This SuperSeries is composed of the following subset Series: GSE31798: DNA copy number profiles of NSCLC tumors GSE31799: Gene expression profiles of NSCLC tumors Refer to individual Series
ORGANISM(S): Homo sapiens 
2011-09-11 | E-GEOD-31800 | biostudies-arrayexpress
TranscriptomicsAn integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer
This SuperSeries is composed of the following subset Series: GSE17768: An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer: gene expression GSE17769: An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant g...
ORGANISM(S): Homo sapiens 
2010-12-31 | E-GEOD-21541 | biostudies-arrayexpress
TranscriptomicsTiling-set aCGH data for oral dysplasias and oral squamous cell carcinomas
Analysis of DNA from 89 oral lesions by whole genome tiling-path array comparative genomic hybridization. Keywords: array comparative genomic hybridization Genomic DNA isolated from 89 formalin-fixed paraffin-embedded oral dysplasias and tumors, then profiled by whole genome tiling-path array CGH to...
ORGANISM(S): Homo sapiens 
2009-07-01 | E-GEOD-11275 | biostudies-arrayexpress
TranscriptomicsAn integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer: CGH
This study was undertaken to identify novel tumour suppressor genes in lung adenocarcinoma. EYA4, located at 6q23.2 was identified as a frequently lost and hypermethylated gene in the analyzed samples. 7 Breast cancer cell lines profiled on the SMRTr array in conjunction with matched DNA methylatio...
ORGANISM(S): Homo sapiens 
2010-12-31 | E-GEOD-21540 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of NSCLC tumors
A custom microarray was used to measure the gene expression of NSCLC tumors. This represents a subset of samples which also have matched DNA copy number profiles from array CGH experiments 49 microdissected NSCLC tumor samples
ORGANISM(S): Homo sapiens 
2011-09-11 | E-GEOD-31799 | biostudies-arrayexpress
TranscriptomicsComprehensive Serial Analysis of Gene Expression of the Cervical Epithelium Transcriptome
In this study, we sequenced 691,390 SAGE tags from four libraries. Cervical L-SAGE libraries N1, N2, C1, and C2 were sequenced to 165,624, 181,224, 173,534, and 171,008 tags, respectively. Duplicate ditags were eliminated from analysis resulting in 136,276, 139,656, 154,828 and 136,386 useful tags...
ORGANISM(S): Homo sapiens 
2008-02-18 | E-GEOD-6252 | biostudies-arrayexpress
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