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MetabolomicsMetabolomic determinants of carotid atherosclerosis plaque stability
Our objective is to identify the metabolites associated with stability of carotid atheromatous plaques compared to vulnerable plaques, through a metabolomic approach. Eighty consecutive patients with carotid artery stenosis (CAS) who underwent carotid endarterectomy (CEA) according to current guidel...
2025-06-06 | MTBLS12303 | MetaboLights
ProteomicsHuman exosome proteome - Human urinary exosomes as innate immune effectors
Proteomics study of human urine exosomes. This data describes the proteomic complement of the human exosomal urine fraction from 10 healthy volunteers (5 male, 5 female) aged 23 to 36 years. 50 µg protein from each sample were fragmented on a 4%/12% SDS-polyacrylamide gel. Following staining, each g...
ORGANISM(S): Homo sapiens (Human) 
2016-08-25 | PXD000117 | Pride
Exosome Urine Human Proteome 
TranscriptomicsIsocitrate dehydrogenase 1 mutations prime the all-trans-retinoic acid myeloid differentiation pathway in acute myeloid leukemia HL-60 cells
Human acute myeloid leukemia HL60 cells were transduced with IDH1-WT or IDH1-R132H, and corresponding sub-clones were generated by FACS. In a first series of experiments, cells expressing wt and mutant IDH1were treated with either 1µM all-trans retinoic acid (ATRA) or with vehicle (DMSO) for 24 hrs...
ORGANISM(S): Homo sapiens 
2017-03-01 | E-MTAB-4327 | biostudies-arrayexpress
UnknownNusG prevents transcriptional invasion of H-NS-silenced genes.
Not available
S-EPMC6797219 | biostudies-literature
TranscriptomicsPhenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice [Expression array].
Evidence suggests that epigenetic perturbations are involved in the adverse effects associated with some drugs and toxicants, including certain classes of non-genotoxic carcinogens. Such epigenetic changes (altered DNA methylation and covalent histone modifications) may take place at the earliest st...
ORGANISM(S): Mus musculus 
2011-12-14 | E-GEOD-34423 | biostudies-arrayexpress
TranscriptomicsP24_STVI_colorectal_cancer_GEX
Focal and temporal tumor heterogeneity can represent a major challenge for biology-guided therapies. This study proposes to investigative molecular discrepancies between primary colorectal cancer samples and matched metastases
ORGANISM(S): Homo sapiens 
2014-12-30 | E-MTAB-2864 | biostudies-arrayexpress
TranscriptomicsP24_STVI_colorectal_cancer_MIR
Focal and temporal tumor heterogeneity can represent a major challenge for biology-guided therapies. This study proposes to investigative molecular discrepancies between primary colorectal cancer samples and matched metastases
ORGANISM(S): Homo sapiens 
2014-12-30 | E-MTAB-2868 | biostudies-arrayexpress
UnknownTreatment of Acquired Deforming Hypertonia with Botulinum Toxin in Older Population: A Retrospective Study.
Not available
S-EPMC11359055 | biostudies-literature
UnknownGenetic diversity of two Daphnia-infecting microsporidian parasites, based on sequence variation in the internal transcribed spacer region.
Not available
S-EPMC4875737 | biostudies-literature
TranscriptomicsTranscription profiling of Drosophila infected with Drosophila C virus reveals a third evolutionary conserved innate immunity pathway operates in drosophila and counters viral infection
The response of drosophila to bacterial and fungal infections involves two signaling pathways, Toll and Imd, which both activate NF-kB family members. We have studied the global transcriptional response of flies to infection with drosophila C virus. Viral infection induced a set of genes distinct fr...
ORGANISM(S): Drosophila melanogaster 
2007-07-07 | E-GEOD-2828 | biostudies-arrayexpress
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