Sort   by:  
 Page size 
MetabolomicsHippophae rhamnoides-Derived Exosome-like Nanovesicles Alleviate Dexamethasone-Induced Sarcopenia by Remodeling Skeletal Muscle Lipid Metabolism
Skeletal muscle atrophy driven by glucocorticoid excess is a clinically relevant contributor to sarcopenia, yet safe and biologically integrated interventions remain limited. Here we report that extracellular exosome-like nanovesicles derived from Hippophae rhamnoides fruits (HR-ELNs) protect agains...
2026-07-17 | MTBLS15070 | MetaboLights
MetabolomicsLC-MS lipidomic characterization of plant-derived exosome-like nanovesicles from ginseng, pueraria lobata, and Chinese yam

This study characterizes the lipid composition of exosome-like nanovesicles isolated from Ginseng, Pueraria lobata, and Chinese yam using LC-MS-based lipidomics. The dataset includes LC-MS raw data and processed lipid annotation and relative quantification tables acquired in both positive and neg...

2026-07-27 | MTBLS14935 | MetaboLights
TranscriptomicsGenome-wide localization of exosome components to active promoters and chromatin insulators in Drosophila
Chromatin insulators are functionally conserved DNA-protein complexes that are situated throughout the genome and organize independent transcriptional domains.  Previous work implicated RNA as an important cofactor in chromatin insulator activity, although the mechanisms by which RNA affects insulat...
ORGANISM(S): Drosophila melanogaster 
2013-01-29 | E-GEOD-41950 | biostudies-arrayexpress
TranscriptomicsExpression data from Drosophila S2 cells depleted of exosome subunits
The exosome complex and its' subunits are vital for proccessing and or degrading many cellular RNAs. We used microarrays to detail the global changes in mRNA levels in response to exosome subunit depletion. RNA was extracted from dsRNA treated S2 cells and hybridized using Affymetrix microarrays. We...
ORGANISM(S): Drosophila melanogaster 
2010-04-12 | E-GEOD-17874 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of thermosensitive exosome mutants from permissive temperature and various time exposure to restrictive temperature
Transcriptome analyses of thermosensitive exosome mutants from permissive temperature to various time exposure to restrictive temperature.
ORGANISM(S): Saccharomyces cerevisiae 
2006-02-28 | E-MEXP-537 | biostudies-arrayexpress
TranscriptomicsTranscriptome-wide Analysis of Exosome Targets in the Budding Yeast Saccharomyces cerevisiae
Purpose: The exosome plays major roles in RNA processing and surveillance but the in vivo target range and substrate acquisition mechanisms remain unclear. We applied an in vivo cross-linking technique coupled with deep sequencing (CRAC) that captures transcriptome-wide interactions between individu...
ORGANISM(S): Saccharomyces cerevisiae 
2012-09-25 | E-GEOD-40046 | biostudies-arrayexpress
TranscriptomicsThe roles of 3’-exoribonucleases and the exosome in trypanosome mRNA degradation
The roles of 3’-exoribonucleases and the exosome in trypanosome mRNA degradation; 30 min after actinomycin D +sinefungin, RNAi against CAf1, CNOT10, PAN2. These are really old data that hadn't been deposited.The datasets called RNA1, RNA2, RNA3 and RNA4 are almost certainly, from their location in t...
ORGANISM(S): Trypanosoma brucei brucei 
2021-03-11 | E-MTAB-10260 | biostudies-arrayexpress
OtherThe nuclear exosome is active and important during budding yeast meiosis.
Data from ProteomeXchange, PXD ID: PXD001239. File: Meiosis_IP_rep.mzml. Published as part of PLoS One. 2014 Sep 11;9(9):e107648 . From the Abstract: {{i}} ... We have analysed the activity of the nuclear exosome during meiosis by deletion of TRF4, which encodes a key component of the exosome targe...
ORGANISM(S): Yeast 
GPM32310019869 | GPMDB
Resource Reanalysis 
TranscriptomicsTumor exosome integrins determine organotropic metastasis
Stephen Paget first proposed, in 1889, that organ distribution of metastases is a non-random event, yet metastatic organotropism remains one of the greatest mysteries in cancer biology. Here, we demonstrate that exosomes released by lung-, liver- and brain-tropic tumor cells fuse preferentially with...
ORGANISM(S): Homo sapiens 
2015-06-17 | E-GEOD-68919 | biostudies-arrayexpress
GenomicsThe RNA Exosome Promotes Transcription Termination of backtracked RNA Polymerase II
Large fractions of genomes are expressed in most eukaryotic cells, generating a diverse repertoire of protein-coding and non-coding transcripts. With such complexity, and as the number of mRNA molecules per cell are often low, it is clear that errors anywhere in the gene expression process could hav...
ORGANISM(S): Schizosaccharomyces pombe 
2014-09-20 | E-MTAB-2237 | biostudies-arrayexpress
Sort   by:  
 Page size