Sort   by:  
 Page size 
TranscriptomicsRelocalization of retinoic acid receptors from non-canonical to canonical spaced binding elements during embryoid body differentiation
Retinoic Acid Receptors (RARs) bind RA-response elements in regulatory regions of their target genes. While canonical RAREs comprise direct repeats of the consensus 5’-RGKTCA-3’ sequence separated by 1, 2 or 5 nucleotides (DR1, DR2, DR5), we show that shortly after RA treatement of mouse embryoid bo...
ORGANISM(S): Mus musculus 
2012-06-15 | E-GEOD-35599 | biostudies-arrayexpress
GenomicsRAR/RXR binding dynamics distinguishes pluripotency from differentiation-associated cis-regulatory elements
In mouse embryonic cells, a retinoic acid (RA) stimulation triggers a massive change of gene expression leading the pluripotent, proliferating cells to a lineage-specific differentiation process. The retinoic acid receptor (RAR) plays a key role in this response by inhibiting pluripotency-maintainin...
ORGANISM(S): Mus musculus 
2015-04-17 | E-GEOD-56893 | biostudies-arrayexpress
Sort   by:  
 Page size