Sort   by:  
 Page size 
Background: Patient derived organoids (PDOs) can be established from colorectal cancers as in vitro models to interrogate cancer biology and its clinical relevance. We applied mass spectrometry (MS) immunopeptidomics to investigate neoantigen presentation and whether this can be augmented through in...
ORGANISM(S): Homo sapiens (Human) 
2019-11-27 | PXD014017 | Pride
Genome editing using CRISPR-Cas systems is a promising avenue for the treatment of genetic diseases. However, cellular and humoral immunogenicity of genome editing tools, which originate from bacteria, complicates their clinical use. Here we report reduced immunogenicity (Red)(i)-variants of two cli...
ORGANISM(S): Homo sapiens (Human) 
2024-11-07 | PXD054579 | Pride
Sort   by:  
 Page size