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ProteomicsCHD6 IP from human induced pluripotent stem cells LC-MS-MS
Members of the chromodomain-helicase-DNA binding (CHD) protein family are chromatin remodelers implicated in human pathologies, with CHD6 being one of its least studied members. We discovered a de novo CHD6 missense mutation in a patient clinically presenting the rare Hallermann-Streiff syndrome (HS...
ORGANISM(S): Homo sapiens (Human) 
2021-03-20 | PXD024803 | Pride
Human ipscs Hallermann-streiff syndrome Chd6 immunoprecipitation Chd6 overexpression Lc-ms/ms 
TranscriptomicsCHD5, A Brain-Specific Chromatin Remodeling Enzyme, Regulates Expression Of Neuronal Genes.
CHD5 is frequently deleted in neuroblastoma, and appears to be a tumor suppressor gene; however, little is known about the role of CHD5. We found CHD5 mRNA was restricted to brain; by contrast most other remodeling ATPases were broadly expressed. CHD5 protein isolated from mouse brain was associat...
ORGANISM(S): Rattus norvegicus 
2011-09-21 | E-GEOD-27620 | biostudies-arrayexpress
TranscriptomicsColorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer
Human colorectal cancer (CRC) cell lines are a used widely-used to model system for investigation investigate of tumour biology, experimental therapytherapeutic and biomarkers discovery. However, to what extent these established CRC cell lines represent and maintain the genetic diversity of primary ...
ORGANISM(S): Homo sapiens 
2015-04-09 | E-GEOD-55832 | biostudies-arrayexpress
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